Am J Psychiatry 1986; 143:1374-1381
Copyright © 1986 by American Psychiatric Association
Lethal catatonia
SC Mann, SN Caroff, HR Bleier, WK Welz, MA Kling and M Hayashida
Lethal catatonia, a life-threatening febrile neuropsychiatric disorder, was
widely reported in this country and abroad before the introduction of
modern psychopharmacologic treatments. A comprehensive review of the world
literature indicates that although the prevalence of lethal catatonia may
have declined, it continues to occur, now reported primarily in the foreign
literature. Lack of recognition probably accounts for the scarcity of
recent American reports. Furthermore, lethal catatonia is a syndrome rather
than a specific disease and may develop in association with both functional
and organic illnesses. Familiarity with the clinical features and varied
etiologies is essential for effective management of this catastrophic
reaction.
