Am J Psychiatry 1978; 135:1549-1552
Copyright © 1978 by American Psychiatric Association
Enuresis treatment with imipramine hydrochloride: a 10-year follow-up study
PM Bindelglas and G Dee
The authors followed 29 young adults who had been treated for enuresis with
imipramine hydrochloride 10 years earlier. To test beliefs that enuresis is
symptomatic of severe psychopathology or of urological conditions, they
studied whether the treatment had been followed by psychological
decompensation; an inhibition of learning; a predisposition to drug abuse;
negative effects on health, growth, weight, and development; or continued
urinary symptoms. None of these negative effects was present; in general
the subjects were active, well- motivated, and sociable and showed no
significant psychiatric symptoms. One patient still wetted but only
occasionally.