Some articles report data that are so precise and revealing that they emphasize how much we have to learn before achieving real understanding. The article by Joel Swendsen and colleagues (6) was one of those. First of all, the topic is of great importance but often overlooked, namely, the comorbidity of drug abuse with schizophrenia. The question focused on the causality of drug use and symptom states in schizophrenia—with a bivalent direction tested. Do negative mood, perceived stress, and psychotic symptoms provoke drug use, or does drug use worsen these symptoms? I was not familiar with use of a “computerized ambulatory monitoring technique” nor a “personal digital assistant” (PDA) in clinical research. The article describes how these authors taught 199 people with schizophrenia to respond to random prompts six times per day for a week asking, each time, about mood, anxiety, psychosis, and drug use. This was successful, on average, 72.1% (SD=19.1%) of the time, a striking response rate. Their data show that the duration of the electronic interview fell progressively over the week, indicating a mastery of the technique by the schizophrenia volunteers. The results showed that 1) sad mood and psychosis tend to provoke drug use, 2) baseline anxiety is a risk factor for continued alcohol use, and 3) any drug use tends to result in increased anxiety and psychosis. Data like these have not been previously obtained because the course of sampling has been so slow that the cause and effect (symptoms/drug use) are effectively dissociated. The development of these clever kinds of techniques to obtain data that we have not previously seen provides hope that we will discover even more important and specific links between drug use and schizophrenia in their future use.