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Postanesthesia Persistent Amnesia in a Patient With a Prior History of Dissociative Fugue State: The Case for the Two-Hit Hypothesis
Inna Roberts, M.D.; Natalie Gluck, M.D.; Michael S. Smith, M.D., M.B.A.; Mary F. Morrison, M.D., M.S.
Am J Psychiatry 2013;170:1398-1400. doi:10.1176/appi.ajp.2013.12121632
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Dr. Smith has served as a consultant for Covidien-GI Solutions, CSA Medical, CDx Laboratories, and NinePoint Medical. Dr. Morrison has received a research grant from AstraZeneca. The other authors report no financial relationships with commercial interests.

From the Departments of Psychiatry and Internal Medicine, Temple University School of Medicine, Philadelphia.

Address correspondence to Dr. Morrison (mary.morrison@tuhs.temple.edu).

Copyright © 2013 by the American Psychiatric Association

Received December 31, 2012; Revised March 21, 2013; Accepted April 22, 2013.


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Quraishi  SA;  Girdharry  TD;  Xu  SG;  Orkin  FK:  Prolonged retrograde amnesia following sedation with propofol in a 12-year-old boy.  Paediatr Anaesth 2007; 17:375–379
[CrossRef] | [PubMed]
Rich  JB;  Yaster  M;  Brandt  J:  Anterograde and retrograde memory in children anesthetized with propofol.  J Clin Exp Neuropsychol 1999; 21:535–546
[CrossRef] | [PubMed]
Masuda  T;  Akatsuka  A;  Kato  S;  Yoshino  A;  Nagashima  S;  Ogawa  S: Retrograde amnesia produced with the use of propofol for sedation for caesarean section. 2005. http://www.eurosiva.org/Archive/Vienna/abstracts/posters/Masuda.htm
Lichtenbelt  BJ;  Olofsen  E;  Dahan  A;  van Kleef  JW;  Struys  MM;  Vuyk  J:  Propofol reduces the distribution and clearance of midazolam.  Anesth Analg 2010; 110:1597–1606
[CrossRef] | [PubMed]
Rinehart  JB;  Baker  B;  Raphael  D:  Postoperative global amnesia reversed with flumazenil.  Neurologist 2012; 18:216–218
[CrossRef] | [PubMed]
Koffman  BM;  Greenfield  LJ;  Ali  II;  Pirzada  NA:  Neurologic complications after surgery for obesity.  Muscle Nerve 2006; 33:166–176
[CrossRef] | [PubMed]
Cirignotta  F;  Manconi  M;  Mondini  S;  Buzzi  G;  Ambrosetto  P:  Wernicke-Korsakoff encephalopathy and polyneuropathy after gastroplasty for morbid obesity: report of a case.  Arch Neurol 2000; 57:1356–1359
[CrossRef] | [PubMed]
McKay  GC;  Kopelman  MD:  Psychogenic amnesia: when memory complaints are medically unexplained.  Adv Psychiatr Treat 2009; 15:152–158
Kikuchi  H;  Fujii  T;  Abe  N;  Suzuki  M;  Takagi  M;  Mugikura  S;  Takahashi  S;  Mori  E:  Memory repression: brain mechanisms underlying dissociative amnesia.  J Cogn Neurosci 2010; 22:602–613
[CrossRef] | [PubMed]
Ren  Y;  Zhang  FJ;  Xue  QS;  Zhao  X;  Yu  BW:  Bilateral inhibition of γ-aminobutyric acid type A receptor function within the basolateral amygdala blocked propofol-induced amnesia and activity-regulated cytoskeletal protein expression inhibition in the hippocampus.  Anesthesiology 2008; 109:775–781
[CrossRef] | [PubMed]
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