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Early identification of renal problems in patients receiving chronic lithium treatment

Published Online:https://doi.org/10.1176/ajp.144.5.670

Serum beta 2-microglobulin and creatinine values were compared with creatinine clearance in 20 lithium-treated patients. beta 2- microglobulin, but not creatinine, correlated significantly with creatinine clearance, indicating that beta 2-microglobulin is a more sensitive test than serum creatinine for monitoring glomerular filtration rate in chronic lithium therapy.

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