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The Possible Thymoleptic Effect of the Lithium Ion

Published Online:https://doi.org/10.1176/ajp.124.10.1452

The authors discuss the possibility that lithium is effective not only against manic states, where it is therapeutically active, but against recurrent depressions, where it acts prophylactically. If it indeed acts against both the polar manifestations of manic-depressive psychosis it would be in a unique position among the psychotropic drugs and warrant a more specific appellation as a mood normalizer or "thymoleptic" agent.

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