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The American Journal of Psychiatry, VOL. 124, No. 10

Articles | April 01, 1968

The Possible Thymoleptic Effect of the Lithium Ion

SAMUEL GERSHON

Am J Psychiatry 1968;124:1452-1456.

Associate professor of psychiatry and chief, neuropsychopharmacology research unit, department of psychiatry, New York University Medical Center, 550 First Avenue, New York, N. Y. 10016

1967-68, American Psychiatric Association

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Abstract

The authors discuss the possibility that lithium is effective not only against manic states, where it is therapeutically active, but against recurrent depressions, where it acts prophylactically. If it indeed acts against both the polar manifestations of manic-depressive psychosis it would be in a unique position among the psychotropic drugs and warrant a more specific appellation as a mood normalizer or "thymoleptic" agent.

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