The sixth chapter examines clinical and rating-scale-based assessment of negative symptoms. Commonly used rating scales, including the Brief Psychiatric Rating Scale, Positive and Negative Syndrome Scale, and Scale for the Assessment of Negative Symptoms, are discussed and included in appendixes. A practical discussion about evaluating and treating causes of "pseudonegative" symptoms is included. The seventh chapter provides a concise review of the effects of atypical antipsychotics. The authors note positive results with clozapine, olanzapine, and risperidone as well as the availability of less evidence recommending quetiapine and ziprasidone. Amisulpride, sulpiride, and zotepine, which are not available in the United States, are discussed, and the authors note that there is good evidence for amisulpride’s effectiveness. Other drugs of interest, including selective serotonin reuptake inhibitors, monoamine oxidase inhibitors, glutamatergic agents, and dopamine agonists are also reviewed.