The first section of the book homes in on the fundamentals of psychopharmacology, covering neurotransmitters, receptors, and the target sites of drug action. The concepts of receptor structure, function, formation, and destruction are illustrated simplistically in an easy to understand fashion. I was especially impressed by the presentation of concepts related to the transporter carrier ion channels, which helped clarify some of my personal doubts. The concepts of down-regulation, up-regulation, and autoreceptor functioning also are presented in an easy to understand fashion. I found the illustrations especially useful in understanding the role of partial agonists, inverse agonists, and partial inverse agonists.