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MAINTENANCE THERAPY OF CHRONIC PSYCHOTICS WITH PERPHENAZINE

Published Online:https://doi.org/10.1176/ajp.120.2.176

Perphenazine was used to treat 300 psychotic patients. The dosage usually ranged between 16 and 4 mg. three times daily, for 1 to 9 months. Remission or significant improvement occurred among 80% of first-admission patients and among 70% of those who had had one or several previous admissions. Mild pseudoparkinsonism during high dosage was the only significant side effect.

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