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American Journal of Psychiatry

Volume 173, Issue 7

July 2016

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Editorials

July 2016

The Value of Repeated Clinical Observation Over Time

Kenneth R. Silk, M.D.

Pages:651–652
Published Online:1 July 2016

https://doi.org/10.1176/appi.ajp.2016.16040484

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July 2016

Mechanisms Distinguishing Irritability in Children and Adolescents

Daniel P. Dickstein, M.D.

Pages:653–654
Published Online:1 July 2016

https://doi.org/10.1176/appi.ajp.2016.16040429

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July 2016

Stress, the Placenta, and Fetal Programming of Behavior: Genes’ First Encounter With the Environment

M. Camille Hoffman, M.D., M.S.C.S.

Pages:655–657
Published Online:1 July 2016

https://doi.org/10.1176/appi.ajp.2016.16050502

First Page
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Treatment in Psychiatry

July 2016

A Framework for Extending Psychiatrists’ Roles in Treating General Health Conditions

Erik R. Vanderlip, M.D., M.P.H.,
Lori E. Raney, M.D.,
Benjamin G. Druss, M.D., M.P.H.

Pages:658–663
Published Online:1 July 2016

https://doi.org/10.1176/appi.ajp.2015.15070950

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Images in Psychiatry

July 2016

Sips of Conflict

Erik Wilkerson, M.S.,
Carolyn Rodriguez, M.D., Ph.D.

Page:664
Published Online:1 July 2016

https://doi.org/10.1176/appi.ajp.2016.16030374

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APA Presidential Addresses

July 2016

Claiming Our Future

Renee Binder, M.D.

Pages:665–667
Published Online:1 July 2016

https://doi.org/10.1176/appi.ajp.2016.173702

First Page
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July 2016

Response to the Presidential Address

Maria A. Oquendo, M.D.

Pages:668–670
Published Online:1 July 2016

https://doi.org/10.1176/appi.ajp.2016.173704

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July 2016

Renee Binder, M.D., 142nd President, 2015–2016

Paul Summergrad, M.D.

Page:671
Published Online:1 July 2016

https://doi.org/10.1176/appi.ajp.2016.173703

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Reviews and Overviews

July 2016

Messages for Clinicians: Moderators and Mediators of Treatment Outcome in Randomized Clinical Trials

Helena Chmura Kraemer, Ph.D.

Pages:672–679
Published Online:17 March 2016

https://doi.org/10.1176/appi.ajp.2016.15101333

Abstract
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Many problems in randomized clinical trial design, execution, analysis, presentation and interpretation stem in part from an inadequate understanding of the roles of moderators and mediators of treatment outcome. As a result, 1) the results of clinical ...

Articles

Video

July 2016

Interpersonal Psychotherapy for Mental Health Problems: A Comprehensive Meta-Analysis

Pim Cuijpers, Ph.D.,
Tara Donker, Ph.D.,
Myrna M. Weissman, Ph.D.,
Paula Ravitz, M.D.,
Ioana A. Cristea, Ph.D.

Pages:680–687
Published Online:1 April 2016

https://doi.org/10.1176/appi.ajp.2015.15091141

Abstract
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Objective:Interpersonal psychotherapy (IPT) has been developed for the treatment of depression but has been examined for several other mental disorders. A comprehensive meta-analysis of all randomized trials examining the effects of IPT for all mental ...

July 2016

Fluidity of the Subsyndromal Phenomenology of Borderline Personality Disorder Over 16 Years of Prospective Follow-Up

Mary C. Zanarini, Ed.D.,
Frances R. Frankenburg, M.D.,
D. Bradford Reich, M.D.,
Garrett M. Fitzmaurice, Sc.D.

Pages:688–694
Published Online:12 February 2016

https://doi.org/10.1176/appi.ajp.2015.15081045

Abstract
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Objective:The purpose of this study was to determine the cumulative rates of 2- and 4-year remission, and the recurrences that follow them, of 24 symptoms of borderline personality disorder over 16 years of prospective follow-up.Method:A total of 290 ...

Video

July 2016

Toward the Definition of a Bipolar Prodrome: Dimensional Predictors of Bipolar Spectrum Disorders in At-Risk Youths

Danella M. Hafeman, M.D., Ph.D.,
John Merranko, M.A.,
David Axelson, M.D.,
Benjamin I. Goldstein, M.D., Ph.D.,
Tina Goldstein, Ph.D.,
Kelly Monk, B.S.N., R.N.,
Mary Beth Hickey, B.A.,
Dara Sakolsky, M.D., Ph.D.,
Rasim Diler, M.D.,
Satish Iyengar, Ph.D.,
David Brent, M.D.,
David Kupfer, M.D.,
Boris Birmaher, M.D.

Pages:695–704
Published Online:19 February 2016

https://doi.org/10.1176/appi.ajp.2015.15040414

Abstract
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Objective:The authors sought to assess dimensional symptomatic predictors of new-onset bipolar spectrum disorders in youths at familial risk of bipolar disorder (“at-risk” youths).Method:Offspring 6–18 years old of parents with bipolar I or II disorder (N=...

July 2016

Distress During Pregnancy: Epigenetic Regulation of Placenta Glucocorticoid-Related Genes and Fetal Neurobehavior

Catherine Monk, Ph.D.,
Tianshu Feng, M.S.,
Seonjoo Lee, Ph.D.,
Izabela Krupska, M.A.,
Frances A. Champagne, Ph.D.,
Benjamin Tycko, M.D., Ph.D.

Pages:705–713
Published Online:25 March 2016

https://doi.org/10.1176/appi.ajp.2015.15091171

Abstract
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Objective:Increased risk of psychopathology is observed in children exposed to maternal prenatal distress, and elevated maternal cortisol and epigenetic regulation of placental glucocorticoid-pathway genes are potential mechanisms. The authors examined ...

July 2016

Phosphodiesterase 10A in Schizophrenia: A PET Study Using [¹¹C]IMA107

Tiago Reis Marques, M.D., Ph.D.,
Sridhar Natesan, M.Pharm., Ph.D.,
Flavia Niccolini, M.D.,
Marios Politis, M.D., Ph.D.,
Roger N. Gunn, Ph.D.,
Graham E. Searle, Ph.D.,
Oliver Howes, M.D., Ph.D.,
Eugenii A. Rabiner, M.B.B.Ch., F.C.Psych.(S.A.),
Shitij Kapur, M.D., Ph.D.

Pages:714–721
Published Online:19 February 2016

https://doi.org/10.1176/appi.ajp.2015.15040518

Abstract
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Objective:Phosphodiesterase 10A (PDE10A) is an enzyme present in striatal medium spiny neurons that degrades the intracellular second messengers triggered by dopamine signaling. The pharmaceutical industry has considerable interest in PDE10A inhibitors ...

July 2016

Neural Correlates of Irritability in Disruptive Mood Dysregulation and Bipolar Disorders

Jillian Lee Wiggins, Ph.D.,
Melissa A. Brotman, Ph.D.,
Nancy E. Adleman, Ph.D.,
Pilyoung Kim, Ph.D.,
Allison H. Oakes, B.A.,
Richard C. Reynolds, M.S.,
Gang Chen, Ph.D.,
Daniel S. Pine, M.D.,
Ellen Leibenluft, M.D.

Pages:722–730
Published Online:19 February 2016

https://doi.org/10.1176/appi.ajp.2015.15060833

Abstract
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Objective:Bipolar disorder and disruptive mood dysregulation disorder (DMDD) are clinically and pathophysiologically distinct, yet irritability can be a clinical feature of both illnesses. The authors examine whether the neural mechanisms mediating ...

Letters to the Editor

July 2016

The Role of Bilateral ECT When Right Unilateral ECT Is Inferior

Charles H. Kellner, M.D.,
Kate G. Farber, B.A.

Page:731
Published Online:1 July 2016

https://doi.org/10.1176/appi.ajp.2016.16020252

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July 2016

Response to Kellner and Farber: Addressing Crossover of High-Dose Right Unilateral ECT to Bitemporal ECT

Declan M. McLoughlin, Ph.D., M.R.C.Psych., on behalf of the authors

Pages:731–732
Published Online:1 July 2016

https://doi.org/10.1176/appi.ajp.2016.16020252r

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July 2016

In Support of Neuroimaging Biomarkers of Treatment Response in First-Episode Schizophrenia

Deepak K. Sarpal, M.D.,
Todd Lencz, Ph.D.,
Anil K. Malhotra, M.D.

Pages:732–733
Published Online:1 July 2016

https://doi.org/10.1176/appi.ajp.2016.16030320

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July 2016

Response to Sarpal et al.: Importance of Neuroimaging Biomarkers for Treatment Development and Clinical Practice

Qiyong Gong, M.D., Ph.D.

Pages:733–734
Published Online:1 July 2016

https://doi.org/10.1176/appi.ajp.2016.16030320r

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July 2016

Potential Regional Differences in GABA Levels in Patients With Psychosis Compared With Control Subjects

Camilo de la Fuente-Sandoval, M.D., Ph.D.

Page:734
Published Online:1 July 2016

https://doi.org/10.1176/appi.ajp.2016.16030261

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July 2016

Response to de la Fuente-Sandoval: Challenges Measuring GABA Levels in Patients With Psychosis

Stefano Marenco, M.D.

Pages:734–735
Published Online:1 July 2016

https://doi.org/10.1176/appi.ajp.2016.16030261r

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Book Forum

July 2016

Rational Suicide, Irrational Laws: Examining Current Approaches to Suicide in Policy and Law

Franklin G. Miller, Ph.D.

Pages:736–737
Published Online:1 July 2016

https://doi.org/10.1176/appi.ajp.2016.16040488

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July 2016

Complementary and Integrative Therapies for Mental Health and Aging

Donovan T. Maust, M.D., M.S.

Pages:737–738
Published Online:1 July 2016

https://doi.org/10.1176/appi.ajp.2016.16040462

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July 2016

Youth Substance Abuse and Co-occurring Disorders

Sean R. LeNoue, M.D.

Page:738
Published Online:1 July 2016

https://doi.org/10.1176/appi.ajp.2016.16040409

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July 2016

Page:739
Published Online:1 July 2016

https://doi.org/10.1176/appi.ajp.2016.1737books

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APA Official Actions

July 2016

Reports to the Membership

Pages:740–750
Published Online:1 July 2016

https://doi.org/10.1176/appi.ajp.2015.173701

Abstract
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The following are edited/abbreviated versions of the annual reports of the APA Secretary, Treasurer, CEO and Medical Director, Speaker, and Speaker-Elect and the chairpersons of the APA Committee on Bylaws, Membership Committee, Committee of Tellers, and ...

Correction

July 2016

Page:735
Published Online:1 July 2016

https://doi.org/10.1176/appi.ajp.2016.1737correction

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