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TRACER IODINE STUDIES ON THYROID ACTIVITY AND THYROID RESPONSIVENESS IN SCHIZOPHRENIA

Published Online:https://doi.org/10.1176/ajp.112.3.170

1. Thyroid activity has been studied by measurement of 24 hours' fractional uptake of tracer dose of I131 in 31 schizophrenics and 35 normal subjects.

2. Following T.S.H. (10 mg.) intramuscular injection, there has been shown to exist a highly significant difference in the normal subjects and the patients in the incremental response of thyroid uptake.

3. Bowman's findings of increased thyroid activity (as measured by I131 uptake) and of lowered B. M. R. in schizophrenics are confirmed here.

4. The possible role of environment is discussed and future studies are outlined.

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