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Emergence of hostility during alprazolam treatment

Published Online:https://doi.org/10.1176/ajp.141.6.792

Of 80 patients given alprazolam, eight became hostile early in treatment. The authors suggest that alprazolam-induced hostility may be more likely in patients with well-suppressed chronic anger and resentment and cite reports of hostility associated with other benzodiazepines.

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