The American Psychiatric Association (APA) has updated its Privacy Policy and Terms of Use, including with new information specifically addressed to individuals in the European Economic Area. As described in the Privacy Policy and Terms of Use, this website utilizes cookies, including for the purpose of offering an optimal online experience and services tailored to your preferences.

Please read the entire Privacy Policy and Terms of Use. By closing this message, browsing this website, continuing the navigation, or otherwise continuing to use the APA's websites, you confirm that you understand and accept the terms of the Privacy Policy and Terms of Use, including the utilization of cookies.

×
ArticleNo Access

Effects of Dextroamphetamine, Chlorpromazine, and Hydroxyzine on Behavior and Performance in Hyperactive Children

Published Online:https://doi.org/10.1176/ajp.129.5.532

In an eight-week double-blind study 61 hyperactive school-age boys were randomly assigned to chlorpromazine, dextroamphetamine, hydroxyzine, or placebo groups. Chlorpromazine and dextroamphetamine, virtually equally effective, were significantly more effective than hydroxyzine in modifying hyperactivity. Dextroamphetamine produced frequent side effects; chlorpromazine did not. The authors suggest that because response to the latter two drugs is highly individualized, final selection must depend upon clinical acumen and perhaps a trial of medication.

Access content

To read the fulltext, please use one of the options below to sign in or purchase access.