A Controlled Study of Nortriptyline and Imipramine
Abstract
A double-blind comparison was made of the secondary amine, nortriptyline, and the tertiary amine, imipramine, in female outpatients with a primary depressive illness. There was no significant difference in the overall response between the two drugs, although other differences were found. It was not possible to confirm clinically the hypothesis that the action of the tertiary amines is medicated through secondary amine derivatives and that tertiary amine configuration is associated with tranquilization and secondary amine configuration with thymoleptic activity.
Access content
To read the fulltext, please use one of the options below to sign in or purchase access.- Personal login
- Institutional Login
- Sign in via OpenAthens
- Register for access
-
Please login/register if you wish to pair your device and check access availability.
Not a subscriber?
PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.
Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).