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Published Online:https://doi.org/10.1176/ajp.126.11.1670

The new major tranquilizer, haloperidol, was compared with fluphenazine in the treatment of disturbed children, most of them schizophrenic. While the overall effectiveness of the two drugs was similar, haloperidol appeared more effective in reducing provocativeness and autism; it also seemed to act more quickly.

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