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Published Online:https://doi.org/10.1176/ajp.117.10.932

It would appear that the incidence and severity of Parkinsonism in this age group is so high that trifluoperazine should be used very cautiously. Occurrence of 1 very dramatic recovery and 3 cases of gratifying improvement suggest that trifluoperazine may be useful in cases of chronic depression resistant to more usual therapies.

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