From the Department of Forensic Psychiatry, University of Eastern Finland, and Niuvanniemi Hospital, Kuopio, Finland; the Department of Clinical Physiology, Kuopio University Hospital, Kuopio; the Finnish Medicines Agency, Kuopio; the Department of Mental Health and Alcohol Research, National Institute for Health and Welfare, Helsinki; the Helsinki Deaconess Institute, Helsinki; the Department of Clinical Neuroscience, Karolinska Institutet, Stockholm; the St. Petersburg Bekhterev Psychoneurological Research Institute and Valdman Institute of Pharmacology, St. Petersburg Pavlov State Medical University, St. Petersburg, Russia.