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The American Journal of Psychiatry

February 01, 2006, Vol. 163, No. 2
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In This Issue
In This Issue
Editorials
Bipolar Disorder Treatment: An Evidence-Based Reality Check
J. Raymond DePaulo, Jr., M.D.
What Is Bipolar Disorder?
Alan C. Swann, M.D.
Pathological Gambling: Focusing on the Addiction, Not the Activity
Carol A. Tamminga, M.D.; Eric J. Nestler, M.D., PH.D.
Psychotherapy in the Journal: What’s Missing?
Glen O. Gabbard, M.D.; Robert Freedman, M.D.
Reviews and Overviews
Why Olanzapine Beats Risperidone, Risperidone Beats Quetiapine, and Quetiapine Beats Olanzapine: An Exploratory Analysis of Head-to-Head Comparison Studies of Second-Generation Antipsychotics
Stephan Heres, M.D.; John Davis, M.D.; Katja Maino, M.D.; Elisabeth Jetzinger, M.D.; Werner Kissling, M.D.; Stefan Leucht, M.D.
Article
Treatment-Resistant Bipolar Depression: A STEP-BD Equipoise Randomized Effectiveness Trial of Antidepressant Augmentation With Lamotrigine, Inositol, or Risperidone
Andrew A. Nierenberg, M.D.; Michael J. Ostacher, M.D., M.P.H.; Joseph R. Calabrese, M.D.; Terence A. Ketter, M.D.; Lauren B. Marangell, M.D.; David J. Miklowitz, Ph.D.; Sachiko Miyahara, M.S.; Mark S. Bauer, M.D.; Michael E. Thase, M.D.; Stephen R. Wisniewski, Ph.D.; Gary S. Sachs, M.D.; STEP-BD Investigators
Predictors of Recurrence in Bipolar Disorder: Primary Outcomes From the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)
Roy H. Perlis, M.D.; Michael J. Ostacher, M.D., M.P.H.; Jayendra K. Patel, M.D.; Lauren B. Marangell, M.D.; Hongwei Zhang, M.D., M.S.; Stephen R. Wisniewski, Ph.D.; Terence A. Ketter, M.D.; David J. Miklowitz, Ph.D.; Michael W. Otto, Ph.D.; Laszlo Gyulai, M.D.; Noreen A. Reilly-Harrington, Ph.D.; Andrew A. Nierenberg, M.D.; Gary S. Sachs, M.D.; Michael E. Thase, M.D.
Clinical Features of Bipolar Depression Versus Major Depressive Disorder in Large Multicenter Trials
Roy H. Perlis, M.D.; Eileen Brown, Ph.D.; Robert W. Baker, M.D.; Andrew A. Nierenberg, M.D.
Risk of Switch in Mood Polarity to Hypomania or Mania in Patients With Bipolar Depression During Acute and Continuation Trials of Venlafaxine, Sertraline, and Bupropion as Adjuncts to Mood Stabilizers
Gabriele S. Leverich, M.S.W., L.C.S.W.-C.; Lori L. Altshuler, M.D.; Mark A. Frye, M.D.; Trisha Suppes, M.D., Ph.D.; Susan L. McElroy, M.D.; Paul E. Keck, Jr., M.D.; Ralph W. Kupka, M.D., Ph.D.; Kirk D. Denicoff, M.D.; Willem A. Nolen, M.D., Ph.D.; Heinz Grunze, M.D.; Maria I. Martinez, M.A.; Robert M. Post, M.D.
Clinical Correlates and Familial Aggregation of Age at Onset in Bipolar Disorder
Ping-I Lin, M.D., Ph.D.; Melvin G. McInnis, M.D.; James B. Potash, M.D., M.P.H.; Virginia Willour, Ph.D.; Dean F. MacKinnon, M.D.; J. Raymond DePaulo, M.D.; Peter P. Zandi, Ph.D.
Randomized, Placebo-Controlled Trial of Olanzapine as Maintenance Therapy in Patients With Bipolar I Disorder Responding to Acute Treatment With Olanzapine
Mauricio Tohen, M.D., Dr.P.H.; Joseph R. Calabrese, M.D.; Gary S. Sachs, M.D.; Michael D. Banov, M.D.; Holland C. Detke, Ph.D.; Richard Risser, M.S.; Robert W. Baker, M.D.; James C.-Y. Chou, M.D.; Charles L. Bowden, M.D.
Risk and Resilience Markers in Bipolar Disorder: Brain Responses to Emotional Challenge in Bipolar Patients and Their Healthy Siblings
Stephanie Krüger, M.D.; Martin Alda, M.D., F.R.C.P.C.; L. Trevor Young, M.D., Ph.D., F.R.C.P.C.; Kim Goldapple, B.S.; Saghar Parikh, M.D., F.R.C.P.C.; Helen S. Mayberg, M.D.
Laboratory-Observed Behavioral Disinhibition in the Young Offspring of Parents With Bipolar Disorder: A High-Risk Pilot Study
Dina R. Hirshfeld-Becker, Ph.D.; Joseph Biederman, M.D.; Aude Henin, Ph.D.; Stephen V. Faraone, Ph.D.; Gabrielle A. Cayton, B.S.; Jerrold F. Rosenbaum, M.D.
Linear Relationship of Valproate Serum Concentration to Response and Optimal Serum Levels for Acute Mania
Michael H. Allen, M.D.; Robert M. Hirschfeld, M.D.; Patricia J. Wozniak, Ph.D.; Jeffrey D. Baker, Ph.D.; Charles L. Bowden, M.D.
Basal Ganglia Shape Alterations in Bipolar Disorder
Jaeuk Hwang, M.D.; In Kyoon Lyoo, M.D., Ph.D.; Stephen R. Dager, M.D.; Seth D. Friedman, Ph.D.; Jung Su Oh, M.S.; Jun Young Lee, M.D.; Seog Ju Kim, M.D.; David L. Dunner, M.D.; Perry F. Renshaw, M.D., Ph.D.
Neurocognitive Function in Unmedicated Manic and Medicated Euthymic Pediatric Bipolar Patients
Mani N. Pavuluri, M.D., Ph.D., F.R.A.N.Z.C.P.; Lindsay S. Schenkel, M.A.; Subhash Aryal, M.S.; Erin M. Harral, B.A.; S. Kristian Hill, Ph.D.; Ellen S. Herbener, Ph.D.; John A. Sweeney, Ph.D.
Autistic Social Impairment in the Siblings of Children With Pervasive Developmental Disorders
John N. Constantino, M.D.; Clara Lajonchere, Ph.D.; Marin Lutz, B.A.; Teddi Gray; Anna Abbacchi, M.S.; Kathleen McKenna; Deepti Singh, B.A.; Richard D. Todd, Ph.D., M.D.
Natural Recovery and Treatment-Seeking in Pathological Gambling: Results of Two U.S. National Surveys
Wendy S. Slutske, Ph.D.
Multicenter Investigation of the Opioid Antagonist Nalmefene in the Treatment of Pathological Gambling
Jon E. Grant, J.D., M.D.; Marc N. Potenza, M.D., Ph.D.; Eric Hollander, M.D.; Renee Cunningham-Williams, Ph.D., M.P.E., L.C.S.W.; Tommi Nurminen, M.Sc.; Gerard Smits, Ph.D.; Antero Kallio, M.D., Ph.D.
Clinical Case Conference
Myocarditis During Clozapine Treatment
David B. Merrill, M.D.; Susanne E. Ahmari, M.D., Ph.D.; Jean-Marie E. Bradford, M.D.; Jeffrey A. Lieberman, M.D.
Brief Report
Lower Switch Rate in Depressed Patients With Bipolar II Than Bipolar I Disorder Treated Adjunctively With Second-Generation Antidepressants
Lori L. Altshuler, M.D.; Trisha Suppes, M.D., Ph.D.; David O. Black, Ph.D.; Willem A. Nolen, M.D.; Gabriele Leverich, M.S.W.; Paul E. Keck, Jr., M.D.; Mark A. Frye, M.D.; Ralph Kupka, M.D.; Susan L. McElroy, M.D.; Heinz Grunze, M.D., Ph.D.; Christina M.R. Kitchen, Ph.D.; Robert Post, M.D.
Differences in Brain Chemistry in Children and Adolescents With Attention Deficit Hyperactivity Disorder With and Without Comorbid Bipolar Disorder: A Proton Magnetic Resonance Spectroscopy Study
Constance M. Moore, Ph.D.; Joseph Biederman, M.D.; Janet Wozniak, M.D.; Eric Mick, Sc.D.; Megan Aleardi, B.A.; Megan Wardrop, B.A.; Meghan Dougherty, B.S.; Terri Harpold, M.D.; Paul Hammerness, M.D.; Edin Randall, B.A.; Perry F. Renshaw, M.D., Ph.D.
Comorbidity in Bipolar Disorder Among the Elderly: Results From an Epidemiological Community Sample
Benjamin I. Goldstein, M.D., Ph.D.; Nathan Herrmann, M.D., F.R.C.P.C.; Kenneth I. Shulman, M.D., F.R.C.P.C.
Evidence of White Matter Pathology in Bipolar Disorder Adolescents Experiencing Their First Episode of Mania: A Diffusion Tensor Imaging Study
Caleb M. Adler, M.D.; John Adams, B.A.; Melissa P. DelBello, M.D.; Scott K. Holland, Ph.D.; Vince Schmithorst, Ph.D.; Ari Levine, B.S.; Kelly Jarvis, B.S.E.; Stephen M. Strakowski, M.D.
Treatment in Psychiatry
New-Onset Bipolar Disorder in Late Life: A Case of Mistaken Identity
David B. Arciniegas, M.D.
Letter to the Editor
Pisa Syndrome in a Patient in a Wheelchair Taking Valproic Acid
MONIQUE YOHANAN, M.D.; JASDEEP S. AULAKH, M.D.; JOANNE WEITH, R.N.; JAMES W. HAWKINS, M.D.
QTc Prolongation and Torsades de Pointes in an Elderly Woman Taking Fluoxetine
INGEBORG WILTING, Pharm.D.; O.M. SMALS, M.D.; N.J. HOLWERDA, M.D.; R.H. MEYBOOM, M.D., Ph.D.; M.L. De BRUIN, Pharm.D., Ph.D.; T.C.G. EGBERTS, Pharm.D., Ph.D.
Am J Psychiatry 2006 163: 326-a-327
NADIA MICALI, M.D., M.R.C.Psych.; ISOBEL HEYMAN, M.B.B.S., Ph.D., M.R.C.Psych.
Comorbidity of Anxiety With Eating Disorders and OCD
NATHALIE GODART, M.D., Ph.D.; SYLVIE BERTHOZ, Ph.D.; FABIENNE PERDEREAU, M.D., M.S.; PHILIPPE JEAMMET, M.D., Ph.D.
Am J Psychiatry 2006 163: 327-327
PER SÖDERSTEN, Ph.D.; CECILIA BERGH, Ph.D.
Dr. Kaye and Colleagues Reply
WALTER H. KAYE, M.D.; CYNTHIA BULIK, Ph.D.; LAURA THORNTON, Ph.D.; KATHERINE PLOTNICOV, Ph.D.
Am J Psychiatry 2006 163: 329-a-329
JITSCHAK G. STOROSUM, M.D., Ph.D.; TAMAR WOHLFARTH, Ph.D.; CHRISTIEN C. GISPEN-de WIED, M.D., Ph.D.; DON H. LINSZEN, M.D., Ph.D.; BETHOLD P.R. GERSONS, M.D., Ph.D.; BARBARA J. van ZWIETEN, Ph.D.; WIM van den BRINK, M.D., Ph.D.
New Mnemonic for Depressive Symptoms
PRAVEEN F. ABRAHAM, D.O.; EDWIN R. SHIRLEY, Ph.D.
Suicide Risk in Placebo-Controlled Trials of Bipolar Disorder
ROBERT D. GOLDNEY, M.D.
Book Forum
The American Psychiatric Publishing Textbook of Suicide Assessment and Management
HERBERT HENDIN, M.D.
Autism Spectrum Disorders: A Research Review for Practitioners
ELISSA P. BENEDEK, M.D.
Late-Life Depression
NORMAN B. LEVY, M.D.
Freud’s Requiem: Mourning, Memory, and the Invisible History of a Summer Walk
PAUL ROAZEN, Ph.D.
Playing Sick? Untangling the Web of Munchausen Syndrome, Munchausen by Proxy, Malingering, and Factitious Disorder
JAMES S. EATON, Jr., M.D.
Images in Psychiatry
Victor Kandinsky, M.D., 1849–1889
Vladimir Lerner, M.D., Ph.D.; Eliezer Witztum, M.D.
Introspections
Piano Sonata in A Major
Richard G. Druss, M.D.
Correction
Correction
Books Received
Books Received
APA Official Actions
APA Council Reports
Editor's Note
New Submission Requirement
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