The American Psychiatric Association (APA) has updated its Privacy Policy and Terms of Use, including with new information specifically addressed to individuals in the European Economic Area. As described in the Privacy Policy and Terms of Use, this website utilizes cookies, including for the purpose of offering an optimal online experience and services tailored to your preferences.

Please read the entire Privacy Policy and Terms of Use. By closing this message, browsing this website, continuing the navigation, or otherwise continuing to use the APA's websites, you confirm that you understand and accept the terms of the Privacy Policy and Terms of Use, including the utilization of cookies.

×
ArticlesFull Access

Selective Effects of Psychotherapy on Frontopolar Cortical Function in PTSD

References

  • 1 Marmar CR, Schlenger W, Henn-Haase C, et al.: Course of posttraumatic stress disorder 40 years after the Vietnam War: findings from the National Vietnam Veterans Longitudinal Study. JAMA Psychiatry 2015; 72:875–881 Crossref, MedlineGoogle Scholar
  • 2 Schnurr PP, Lunney CA, Bovin MJ, et al.: Posttraumatic stress disorder and quality of life: extension of findings to veterans of the wars in Iraq and Afghanistan. Clin Psychol Rev 2009; 29:727–735 Crossref, MedlineGoogle Scholar
  • 3 Cusack K, Jonas DE, Forneris CA, et al.: Psychological treatments for adults with posttraumatic stress disorder: a systematic review and meta-analysis. Clin Psychol Rev 2016; 43:128–141 Crossref, MedlineGoogle Scholar
  • 4 Foa EB, Gillihan SJ, Bryant RA: Challenges and successes in dissemination of evidence-based treatments for posttraumatic stress: lessons learned from prolonged exposure therapy for PTSD. Psychol Sci Public Interest 2013; 14:65–111 Crossref, MedlineGoogle Scholar
  • 5 Foa EB, Hembree EA, Rothbaum BO: Prolonged Exposure Therapy for PTSD. Oxford, UK, Oxford University Press, 2007 Google Scholar
  • 6 Foa EB, Kozak MJ: Emotional processing of fear: exposure to corrective information. Psychol Bull 1986; 99:20–35 Crossref, MedlineGoogle Scholar
  • 7 Bohning DE, Shastri A, McGavin L, et al.: Motor cortex brain activity induced by 1-Hz transcranial magnetic stimulation is similar in location and level to that for volitional movement. Invest Radiol 2000; 35:676–683 Crossref, MedlineGoogle Scholar
  • 8 Levin P, Lazrove S, van der Kolk B: What psychological testing and neuroimaging tell us about the treatment of posttraumatic stress disorder by eye movement desensitization and reprocessing. J Anxiety Disord 1999; 13:159–172 Crossref, MedlineGoogle Scholar
  • 9 Lansing K, Amen DG, Hanks C, et al.: High-resolution brain SPECT imaging and eye movement desensitization and reprocessing in police officers with PTSD. J Neuropsychiatry Clin Neurosci 2005; 17:526–532 Crossref, MedlineGoogle Scholar
  • 10 Peres JF, Newberg AB, Mercante JP, et al.: Cerebral blood flow changes during retrieval of traumatic memories before and after psychotherapy: a SPECT study. Psychol Med 2007; 37:1481–1491 Crossref, MedlineGoogle Scholar
  • 11 Lindauer RJ, Booij J, Habraken JB, et al.: Effects of psychotherapy on regional cerebral blood flow during trauma imagery in patients with post-traumatic stress disorder: a randomized clinical trial. Psychol Med 2008; 38:543–554 Crossref, MedlineGoogle Scholar
  • 12 Aupperle RL, Allard CB, Simmons AN, et al.: Neural responses during emotional processing before and after cognitive trauma therapy for battered women. Psychiatry Res 2013; 214:48–55 Crossref, MedlineGoogle Scholar
  • 13 Rabe S, Zoellner T, Beauducel A, et al.: Changes in brain electrical activity after cognitive behavioral therapy for posttraumatic stress disorder in patients injured in motor vehicle accidents. Psychosom Med 2008; 70:13–19 Crossref, MedlineGoogle Scholar
  • 14 Thomaes K, Dorrepaal E, Draijer N, et al.: Treatment effects on insular and anterior cingulate cortex activation during classic and emotional Stroop interference in child abuse-related complex post-traumatic stress disorder. Psychol Med 2012; 42:2337–2349 Crossref, MedlineGoogle Scholar
  • 15 Felmingham K, Kemp A, Williams L, et al.: Changes in anterior cingulate and amygdala after cognitive behavior therapy of posttraumatic stress disorder. Psychol Sci 2007; 18:127–129 Crossref, MedlineGoogle Scholar
  • 16 Peres JF, Foerster B, Santana LG, et al.: Police officers under attack: resilience implications of an fMRI study. J Psychiatr Res 2011; 45:727–734 Crossref, MedlineGoogle Scholar
  • 17 Roy MJ, Francis J, Friedlander J, et al.: Improvement in cerebral function with treatment of posttraumatic stress disorder. Ann N Y Acad Sci 2010; 1208:142–149 Crossref, MedlineGoogle Scholar
  • 18 Brooks SJ, Stein DJ: A systematic review of the neural bases of psychotherapy for anxiety and related disorders. Dialogues Clin Neurosci 2015; 17:261–279 MedlineGoogle Scholar
  • 19 Etkin A, Klemenhagen KC, Dudman JT, et al.: Individual differences in trait anxiety predict the response of the basolateral amygdala to unconsciously processed fearful faces. Neuron 2004; 44:1043–1055 Crossref, MedlineGoogle Scholar
  • 20 Etkin A, Schatzberg AF: Common abnormalities and disorder-specific compensation during implicit regulation of emotional processing in generalized anxiety and major depressive disorders. Am J Psychiatry 2011; 168:968–978 LinkGoogle Scholar
  • 21 Minkel JD, McNealy K, Gianaros PJ, et al.: Sleep quality and neural circuit function supporting emotion regulation. Biol Mood Anxiety Disord 2012; 2:22 Crossref, MedlineGoogle Scholar
  • 22 Chen AC, Oathes DJ, Chang C, et al.: Causal interactions between fronto-parietal central executive and default-mode networks in humans. Proc Natl Acad Sci USA 2013; 110:19944–19949 Crossref, MedlineGoogle Scholar
  • 23 Shannon CE: A mathematical theory of communication. Bell System Technical Journal 1948; 27:379–423 CrossrefGoogle Scholar
  • 24 Wang Z, Li Y, Childress AR, et al.: Brain entropy mapping using fMRI. PLoS One 2014; 9:e89948 Crossref, MedlineGoogle Scholar
  • 25 Shuiabi E, Thomson V, Bhuiyan N: Entropy as a measure of operational flexibility. Eur J Oper Res 2005; 165:696–707 CrossrefGoogle Scholar
  • 26 Kraemer HC, Wilson GT, Fairburn CG, et al.: Mediators and moderators of treatment effects in randomized clinical trials. Arch Gen Psychiatry 2002; 59:877–883 Crossref, MedlineGoogle Scholar
  • 27 McLaren DG, Ries ML, Xu G, et al.: A generalized form of context-dependent psychophysiological interactions (gPPI): a comparison to standard approaches. Neuroimage 2012; 61:1277–1286 Crossref, MedlineGoogle Scholar
  • 28 Daw ND, O’Doherty JP, Dayan P, et al.: Cortical substrates for exploratory decisions in humans. Nature 2006; 441:876–879 Crossref, MedlineGoogle Scholar
  • 29 Burgess PW, Dumontheil I, Gilbert SJ: The gateway hypothesis of rostral prefrontal cortex (area 10) function. Trends Cogn Sci 2007; 11:290–298 Crossref, MedlineGoogle Scholar
  • 30 Turner MS, Simons JS, Gilbert SJ, et al.: Distinct roles for lateral and medial rostral prefrontal cortex in source monitoring of perceived and imagined events. Neuropsychologia 2008; 46:1442–1453 Crossref, MedlineGoogle Scholar
  • 31 Ramnani N, Owen AM: Anterior prefrontal cortex: insights into function from anatomy and neuroimaging. Nat Rev Neurosci 2004; 5:184–194 Crossref, MedlineGoogle Scholar
  • 32 Milad MR, Rosenbaum BL, Simon NM: Neuroscience of fear extinction: implications for assessment and treatment of fear-based and anxiety related disorders. Behav Res Ther 2014; 62:17–23 Crossref, MedlineGoogle Scholar
  • 33 Buhle JT, Silvers JA, Wager TD, et al.: Cognitive reappraisal of emotion: a meta-analysis of human neuroimaging studies. Cereb Cortex 2014; 24:2981–2990 Crossref, MedlineGoogle Scholar
  • 34 Fonzo GA, Goodkind MS, Oathes DJ, et al.: PTSD psychotherapy outcome predicted by brain activation during emotional reactivity and regulation. Am J Psychiatry 2017; 174:1163–1174 LinkGoogle Scholar
  • 35 Messina I, Sambin M, Palmieri A, et al.: Neural correlates of psychotherapy in anxiety and depression: a meta-analysis. PLoS One 2013; 8:e74657 Crossref, MedlineGoogle Scholar
  • 36 Seeley WW, Menon V, Schatzberg AF, et al.: Dissociable intrinsic connectivity networks for salience processing and executive control. J Neurosci 2007; 27:2349–2356 Crossref, MedlineGoogle Scholar
  • 37 Yarkoni T, Poldrack RA, Nichols TE, et al.: Large-scale automated synthesis of human functional neuroimaging data. Nat Methods 2011; 8:665–670 Crossref, MedlineGoogle Scholar
  • 38 Kalisch R: The functional neuroanatomy of reappraisal: time matters. Neurosci Biobehav Rev 2009; 33:1215–1226 Crossref, MedlineGoogle Scholar
  • 39 Patel R, Spreng RN, Shin LM, et al.: Neurocircuitry models of posttraumatic stress disorder and beyond: a meta-analysis of functional neuroimaging studies. Neurosci Biobehav Rev 2012; 36:2130–2142 Crossref, MedlineGoogle Scholar
  • 40 Critchley HD, Nagai Y, Gray MA, et al.: Dissecting axes of autonomic control in humans: insights from neuroimaging. Auton Neurosci 2011; 161:34–42 Crossref, MedlineGoogle Scholar
  • 41 Wager TD, Davidson ML, Hughes BL, et al.: Prefrontal-subcortical pathways mediating successful emotion regulation. Neuron 2008; 59:1037–1050 Crossref, MedlineGoogle Scholar
  • 42 Burgess PW, Gilbert SJ, Dumontheil I: Function and localization within rostral prefrontal cortex (area 10). Philos Trans R Soc Lond B Biol Sci 2007; 362:887–899 Crossref, MedlineGoogle Scholar
  • 43 Kilts CD, Kelsey JE, Knight B, et al.: The neural correlates of social anxiety disorder and response to pharmacotherapy. Neuropsychopharmacology 2006; 31:2243–2253 Crossref, MedlineGoogle Scholar
  • 44 Klumpp H, Fitzgerald DA, Phan KL: Neural predictors and mechanisms of cognitive behavioral therapy on threat processing in social anxiety disorder. Prog Neuropsychopharmacol Biol Psychiatry 2013; 45:83–91 Crossref, MedlineGoogle Scholar
  • 45 Nahas Z, Anderson BS, Borckardt J, et al.: Bilateral epidural prefrontal cortical stimulation for treatment-resistant depression. Biol Psychiatry 2010; 67:101–109 Crossref, MedlineGoogle Scholar
  • 46 Yamanishi T, Nakaaki S, Omori IM, et al.: Changes after behavior therapy among responsive and nonresponsive patients with obsessive-compulsive disorder. Psychiatry Res 2009; 172:242–250 Crossref, MedlineGoogle Scholar
  • 47 Nagai Y, Critchley HD, Featherstone E, et al.: Activity in ventromedial prefrontal cortex covaries with sympathetic skin conductance level: a physiological account of a “default mode” of brain function. Neuroimage 2004; 22:243–251 Crossref, MedlineGoogle Scholar