Editors

Dan G. Blazer, M.D., Ph.D.
J.P. Gibbons Professor of Psychiatry and Behavioral Sciences and Professor of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina

David C. Steffens, M.D., M.H.S.
Professor of Psychiatry and Head, Division of Geriatric Psychiatry, Duke University Medical Center, Durham, North Carolina

Contributors

Marc E. Agronin, M.D.
Director of Mental Health Services, Miami Jewish Home & Hospital for the Aged; Associate Professor of Psychiatry, University of Miami Miller School of Medicine, Miami, Florida

Deborah K. Attix, Ph.D.
Associate Professor of Medical Psychology, Department of Psychiatry and Behavioral Sciences, and Director, Clinical Neuropsychology Service, Division of Neurology, Duke University Medical Center, Durham, North Carolina

Connie Watkins Bales, Ph.D., R.D.
Associate Director, Geriatrics Research, Education, and Clinical Center, Durham VA Medical Center; Associate Professor, Department of Medicine, Duke University Medical Center, Durham, North Carolina

John L. Beyer, M.D.
Assistant Professor of Psychiatry, Duke University Medical Center, Durham, North Carolina

Dan G. Blazer, M.D., Ph.D.
J.P. Gibbons Professor of Psychiatry and Behavioral Sciences and Professor of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina

Elise J. Bolda, M.S.P.H., Ph.D.
Associate Research Professor and Director, NPO Institute for Health Policy, University of Southern Maine, Portland, Maine

Patrick S. Calhoun, Ph.D.
Clinical Assistant Professor, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center; Staff Psychologist, Durham VA Medical Center; Health Services Research Core Director, VA Mid- Atlantic Mental Illness Research, Education, and Clinical Center, Durham, North Carolina

Steven S. Chin, M.D., Ph.D.
Associate Professor of Pathology and Neurology and Director of Neuropathology, Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, Utah

Peggye Dilworth-Anderson, Ph.D.
Professor, Health Policy and Administration/School of Public Health, and Associate Director, UNC Institute on Aging, University of North Carolina, Chapel Hill

P. Murali Doraiswamy, M.D.
Associate Professor of Psychiatry and Chief, Division of Biological Psychiatry, Duke University Medical Center, Durham, North Carolina

Jack D. Edinger, Ph.D.
Senior Psychologist, Durham VA Medical Center; Clinical Professor, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina

Michael A. Fearing, Ph.D.
Postdoctoral Research Fellow, Aging Brain Center, Institute for Aging Research, Hebrew SeniorLife; Fellow in Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts

Linda K. George, Ph.D.
Professor of Sociology and Associate Director, Center for the Study of Aging and Human Development, Duke University, Durham, North Carolina

Harold W. Goforth, M.D.
Assistant Professor of Psychiatry, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina

Lisa P. Gwyther, M.S.W.
Associate Clinical Professor, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina

Judith C. Hays, R.N., Ph.D.
Associate Professor, Duke University School of Nursing, Center for the Study of Aging and Human Development, Durham, North Carolina

Celia F. Hybels, Ph.D.
Assistant Professor, Department of Psychiatry and Behavioral Sciences, Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, North Carolina

Sharon K. Inouye, M.D., M.P.H.
Director and Milton and Shirley F. Levy Family Chair, Aging Brain Center, Institute for Aging Research, Hebrew SeniorLife; Professor of Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts

Dilip V. Jeste, M.D.
Estelle and Edgar Levi Chair in Aging; Director, Sam and Rose Stein Institute for Research on Aging; and Distinguished Professor of Psychiatry and Neurosciences, University of California, San Diego; Chief, Division of Geriatric Psychiatry, VA San Diego Healthcare System, San Diego, California

Robert M. Kaiser, M.D., M.H.Sc.
Associate Professor of Clinical Medicine, Division of Gerontology and Geriatric Medicine; University of Miami Miller School of Medicine; Geriatric Research, Education and Clinical Center Investigator, Miami VA GRECC, Miami, Florida

Jason H.T. Karlawish, M.D.
Associate Professor, Departments of Internal Medicine and Medical Ethics, University of Pennsylvania, Philadelphia, Pennsylvania

Ira R. Katz, M.D., Ph.D.
Professor of Psychiatry, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania

Jason D. Kilts, Ph.D.
Senior Research Associate, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center; Durham VA Medical Center, Durham, North Carolina

Harold G. Koenig, M.D., M.H.Sc.
Professor of Psychiatry and Behavioral Sciences and Associate Professor of Medicine, Duke University, Durham, North Carolina

Andrew D. Krystal, M.D., M.S.
Director, Sleep Research Laboratory, and Associate Professor, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina

Nicole M. Lanouette, M.D.
Postdoctoral Research Fellow, Department of Psychiatry, University of California, San Diego, VA San Diego Healthcare System, San Diego, California

Eric J. Lenze, M.D.
Associate Professor of Psychiatry, Washington University School of Medicine, St. Louis, Missouri

J. Pierre Loebel, M.D.
Clinical Professor Emeritus of Psychiatry, Department of Psychiatry, University of Washington, Seattle, Washington

Constantine G. Lyketsos, M.D., M.H.S.
The Elizabeth Plank Althouse Professor and Chair of Psychiatry for Johns Hopkins Bayview, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland

Thomas R. Lynch, Ph.D.
Professor of Clinical Psychology, Mood Disorders Centre, School of Psychology, University of Exeter, and Academic Lead, Human Sciences, Peninsula College of Medicine and Dentistry, Exeter, United Kingdom

David J. Madden, Ph.D.
Professor of Medical Psychology, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina

George L. Maddox, Ph.D.
Professor Emeritus, Department of Sociology, and Program Director, Long Term Care Resources Program, Duke University Medical Center, Durham, North Carolina

Peter Martin, Ph.D.
Professor, Human Development and Family Studies, and Director, Gerontology Program, Iowa State University, Ames, Iowa

Christine E. Marx, M.D., M.A.
Associate Professor, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center; Staff Psychiatrist, Durham VA Medical Center; Clinical Interventions Core Director, VA Mid-Atlantic Mental Illness Research, Education, and Clinical Center, Durham, North Carolina

Shahrzad Mavandadi, Ph.D.
Investigator, Philadelphia VA Medical Center VISN 4 Mental Illness Research, Education, and Clinical Center, Philadelphia, Pennsylvania

Diane E. Meglin, M.S.W.
Medical Instructor, Clinical Social Workers, Duke University Medical Center, Durham, North Carolina

Scott D. Moore, M.D., Ph.D.
Associate Professor of Biological Psychiatry, Duke University Medical Center, Durham, North Carolina

Benoit H. Mulsant, M.D.
Clinical Director, Geriatric Mental Health Program, and Physician in Chief, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Professor and Vice-Chair, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada

Jennifer C. Naylor, Ph.D.
Research Associate, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center; Durham VA Medical Center; Mid-Atlantic Mental Illness Research, Education, and Clinical Center, Durham, North Carolina

David W. Oslin, M.D.
Associate Professor, University of Pennsylvania and Philadelphia VA Medical Center VISN 4 Mental Illness Research, Education, and Clinical Center, Philadelphia, Pennsylvania

Thomas E. Oxman, M.D.
Professor Emeritus of Psychiatry, Dartmouth Medical School, Lebanon, New Hampshire

Martha Elizabeth Payne, Ph.D., R.D., M.P.H.
Assistant Professor, Department of Psychiatry and Behavioral Sciences, Duke University, Durham, North Carolina

Victoria M. Payne, M.D.
Psychiatry Research Fellow, Durham VA Medical Center; VA Mid-Atlantic Mental Illness Research, Education, and Clinical Center, Durham, North Carolina

Bruce G. Pollock, M.D., Ph.D.
Vice President, Research, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Sandra A. Rotman Chair in Neuropsychiatry, Rotman Research Institute, Toronto, Ontario, Canada; Professor and Head, Division of Geriatric Psychiatry, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

Leonard W. Poon, Ph.D.
Professor of Public Health and Psychology and Director, Institute of Gerontology and the Georgia Geriatric Education Center, College of Public Health, The University of Georgia, Athens, Georgia

William E. Reichman, M.D.
Professor of Psychiatry, Baycrest Centre for Geriatric Care and Department of Psychiatry, University of Toronto, Ontario, Canada

K. Warner Schaie, Ph.D., Sc.D. (hon.), Dr.Phil.H.C.
Evan Pugh Professor of Human Development and Psychology, Pennsylvania State University, University Park; Affiliate Professor of Psychiatry and Behavioral Science, University of Washington, Seattle

Burton Scott, Ph.D., M.D.
Associate Clinical Professor, Division of Neurology, Department of Medicine; Duke University Movement Disorders Clinic, Duke University Medical Center, Durham, North Carolina

Ilene C. Siegler, Ph.D., M.P.H.
Professor of Medical Psychology, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, and Professor of Psychology and Neuroscience, Duke University, Durham, North Carolina; Adjunct Professor of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, North Carolina

Moria J. Smoski, Ph.D.
Clinical Associate, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina

David C. Steffens, M.D., M.H.Sc.
Professor of Psychiatry and Head, Division of Geriatric Psychiatry, Duke University Medical Center, Durham, North Carolina

Jennifer L. Strauss, Ph.D.
Assistant Professor, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center; Durham VA Medical Center; VA Mid-Atlantic Mental Illness Research, Education, and Clinical Center, Durham, North Carolina

Joel E. Streim, M.D.
Professor of Psychiatry, Department of Psychiatry, University of Pennsylvania; VISN 4 Mental Illness Research, Education, and Clinical Center, Philadelphia VA Medical Center, Philadelphia, Pennsylvania

Robert A. Sweet, M.D.
Professor of Psychiatry and Neurology, University of Pittsburgh; Co-Associate Director for Research, Mental Illness Research, Education, and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania

Warren D. Taylor, M.D.
Associate Professor of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina

Mugdha Thakur, M.D.
Assistant Professor of Psychiatry, Duke University Medical Center, Durham, North Carolina

Larry W. Thompson, Ph.D.
Professor of Medicine (Research), Emeritus, Stanford University School of Medicine, Stanford, California

Ipsit V. Vahia, M.D.
Stein Institute for Research on Aging, Department of Psychiatry, University of California, San Diego; VA San Diego Healthcare System, San Diego, California

Richard D. Weiner, M.D., Ph.D.
Professor, Department of Psychiatry and Behavioral Sciences, Duke University Medical School; Chief, Mental Health Service Line, Durham VA Medical Center, Durham, North Carolina

Kathleen A. Welsh-Bohmer, Ph.D.
Professor of Medical Psychology, Department of Psychiatry, and Director, Joseph and Kathleen Bryan Alzheimer's Disease Research Center, Division of Neurology, Department of Medicine, Duke University Medical Center, Durham, North Carolina

Julie Loebach Wetherell, Ph.D.
Associate Professor of Psychiatry, University of California, San Diego; Staff Psychologist, VA San Diego Healthcare System, San Diego, California

Patricia A. Wilkosz, M.D., Ph.D.
Postdoctoral Research Scholar, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

Sherry L. Willis, Ph.D.
Professor of Human Development, The Pennsylvania State University, University Park; Affiliate Research Professor, Department of Psychiatry, University of Washington, Seattle

William K. Wohlgemuth, Ph.D.
Research Associate Professor, Departments of Psychology and Neurology, University of Miami, Miami, Florida

Disclosure of Interests

The following contributors to this book have indicated a financial interest in or other affiliation with a commercial supporter, a manufacturer of a commercial product, a provider of a commercial service, a nongovernmental organization, and/or a government agency, as listed below:

Marc E. Agronin, M.D. Research support: Elan, Forest, Novo Nordisk, Ono, Ortho Biotech, Solvay, Takeda. Speaker's bureau: Abbott, AstraZeneca, Forest, Janssen, Ortho-McNeil Neurologics.

John L. Beyer, M.D. Advisory committee: Eli Lilly. Research support: Bristol-Myers Squibb, Eisai, Elan, Eli Lilly, GlaxoSmithKline, Myriad Genetics, National Institute of Mental Health, Novartis, Pfizer, Sanofi-Aventis. Speaker's bureau: Bristol-Myers Squibb, Eli Lilly, Pfizer.

P. Murali Doraiswamy, M.D. Honoraria: Alzheimer Foundation of America, American Psychiatric Association, AVID, Eli Lilly, Forest, Myriad Genetics, Otsuka/Bristol Myers-Squibb, National Institutes of Health, Neuroptix, Wyeth. Research support: AVID, Boehringer-Ingelheim, Eisai, Elan, GlaxoSmithKline, Myriad Genetics, National Institutes of Health, Novartis, Pfizer, Sanofi, University of California. Equities: Fidelity (403), Sonexa.

Jack D. Edinger, Ph.D. Consulting: Philips Respironics. Honorarium: Takeda. Research support: Helicor, Philips Respironics. Speaker's bureau: Sleep Medicine Education Institute.

Harold W. Goforth, M.D. Consulting: Bristol-Myers Squibb. Research support: Forest, Sepracor.

Dilip V. Jeste, M.D. Consulting: Bristol-Myers Squibb, Otsuka, Solvay, Wyeth. Donations: AstraZeneca, Bristol-Myers Squibb, and Eli Lilly donate antipsychotic medications for the NIMH-funded R01 grant “Metabolic Effects of Newer Antipsychotics in Older Patients.” Research support: Department of Veterans Affairs, National Institute of Mental Health (grant MH66248).

Eric J. Lenze, M.D. Research support: Forest Research Institute, Ortho-McNeil Neurologics, Pfizer.

Constantine G. Lyketsos, M.D., M.H.S. Continuing medical education support, honoraria, research support, and travel support: Bristol-Myers Squibb, Forest, GlaxoSmithKline, Janssen, Johnson & Johnson, Novartis, Ortho, Pfizer.

Christine E. Marx, M.D., M.A. Donations: Bristol-Myers Squibb, study drug and matching placebo for a randomized, controlled trial of aripiprazole in posttraumatic stress disorder. Patent application (provisional): “Neurosteroid Compositions and Methods of Use Therefor.”

Benoit H. Mulsant, M.D. [1999–2006 interests] Consulting: AstraZeneca, Bristol-Myers Squibb, Eli Lilly, Forest, Fox Learning System, GlaxoSmithKline, Janssen, Lundbeck Research, Pfizer. Honoraria: AstraZeneca, Eisai, Forest, Janssen, Lundbeck Research, GlaxoSmithKline, Pfizer. Research support: AstraZeneca, Corcept, Eisai, Eli Lilly, Forest, GlaxoSmithKline, Janssen, National Institutes of Health (current), Pfizer (current). Equities (as of April 2008): AkzoNobel, Alkermes, AstraZeneca, Biogen Idec, Celsion, Elan, Eli Lilly, Forest, General Electric, Orchestra Therapeutics. Other material or financial support: Forest, Janssen.

Bruce G. Pollock, M.D., Ph.D. Advisory board: Forest Laboratories, Takeda. Research support: Janssen, National Institutes of Health.

Burton Scott, Ph.D., M.D. Research support: Boehringer-Ingelheim, Cephalon, GlaxoSmithKline, Merz, Schwarz, Teva. Speaker's bureau: Boehringer-Ingelheim, GlaxoSmithKline, UCB.

Warren D. Taylor, M.D. Research support: National Institutes of Health.

Julie Loebach Wetherell, Ph.D. Research support: Forest Laboratories.

The following authors have no competing interests to report:

Deborah K. Attix, Ph.D.
Connie Watkins Bales, Ph.D., R.D.
Dan G. Blazer, M.D., Ph.D.
Elise J. Bolda, M.S.P.H., Ph.D.
Patrick S. Calhoun, Ph.D.
Steven S. Chin, M.D., Ph.D.
Peggye Dilworth-Anderson, Ph.D.
Michael A. Fearing, Ph.D.
Linda K. George, Ph.D.
Lisa P. Gwyther, M.S.W.
Judith C. Hays, R.N., Ph.D.
Celia F. Hybels, Ph.D.
Sharon K. Inouye, M.D., M.P.H.
Robert M. Kaiser, M.D., M.H.Sc.
Jason H.T. Karlawish, M.D.
Ira R. Katz, M.D., Ph.D.
Jason D. Kilts, Ph.D.
Harold G. Koenig, M.D., M.H.Sc.
Andrew D. Krystal, M.D., M.S.
Nicole M. Lanouette, M.D.
J. Pierre Loebel, M.D.
Thomas R. Lynch, Ph.D.
David J. Madden, Ph.D.
George L. Maddox, Ph.D.
Peter Martin, Ph.D.
Shahrzad Mavandadi, Ph.D.
Diane E. Meglin, M.S.W.
Scott D. Moore, M.D., Ph.D.
Jennifer C. Naylor, Ph.D.
David W. Oslin, M.D.
Thomas E. Oxman, M.D.
Martha Elizabeth Payne, Ph.D., R.D., M.P.H.
Victoria M. Payne, M.D.
Leonard W. Poon, Ph.D.
William E. Reichman, M.D.
K. Warner Schaie, Ph.D., Sc.D. (hon.), Dr.Phil.H.C.
Ilene C. Siegler, Ph.D., M.P.H.
Moria J. Smoski, Ph.D.
David C. Steffens, M.D., M.H.Sc.
Jennifer L. Strauss, Ph.D.
Joel E. Streim, M.D.
Robert A. Sweet, M.D.
Mugdha Thakur, M.D.
Larry W. Thompson, Ph.D.
Ipsit V. Vahia, M.D.
Richard D. Weiner, M.D., Ph.D.
Kathleen A. Welsh-Bohmer, Ph.D.
Patricia A. Wilkosz, M.D., Ph.D.
Sherry L. Willis, Ph.D.
William K. Wohlgemuth, Ph.D