July 01, 2012
AJP CME Course for July 2012: Genetic Variation in KCNH2 Associated With Expression in the Brain of a Unique hERG Isoform Modulates Treatment Response in Patients With Schizophrenia

Self-Assessment Quiz - Expired

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The potassium channel gene KCNH2 is of interest as a factor in the response of patients to antipsychotic drugs for the following reasons:
The authors assessed genotype effect on time to discontinuation in the olanzapine response data; they found that individuals with TT genotypes at rs1036145 had which of the following outcomes compared with nonrisk allele homozygous individuals?
The association of KCNH2 genotype with antipsychotic treatment suggests that patients who respond best have: