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May 01, 2009
Neurobiology of Alzheimer's Disease
Expires May 31, 2015
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CME Activity

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Sample questions:
1.
Alzheimer’s disease (AD) is characterized by pathological changes in the brain. Which of the following are intracellular accumulations of hyperphosphorylated tau?
2.
Abundant evidence suggests that the clinical syndrome of Alzheimer’s disease (AD) involves failed neurotransmission at synapses in the neocortex and hippocampus. What type of synapses are these?
3.
Currently, the standard treatment for the cognitive decline that occurs with Alzheimer’s disease (AD) has been the use of acetylcholinesterase inhibitors. However, the improvement produced by these medications has been modest. Current research has focused on the development of cholinergic agonists and, in particular, agents that bind on one of the subtypes of the muscarinic acetylcholine (mACh) receptor. Xanomeline is one of these new agents, and it binds at which of the mACh receptors?