Am J Psychiatry 1982; 139:1136-1139
Copyright © 1982 by American Psychiatric Association

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The Global Deterioration Scale for assessment of primary degenerative dementia

B Reisberg, SH Ferris, MJ de Leon and T Crook

Cognitive decline associated with old age and consistent with the diagnosis of primary degenerative dementia is a unique clinical syndrome with characteristic phenomena and progression. The authors describe a Global Deterioration Scale for the assessment of primary degenerative dementia and delineation of its stages. The authors have used the Global Deterioration Scale successfully for more than 5 years and have validated it against behavioral, neuroanatomic, and neurophysiologic measures in patients with primary degenerative dementia.

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