Am J Psychiatry 1986; 143:503-507
Copyright © 1986 by American Psychiatric Association
Reduced TSH and prolactin responses to TRH in patients with panic disorder
PP Roy-Byrne, TW Uhde, DR Rubinow and RM Post
The authors studied the TSH and prolactin responses to a standard 500-
micrograms thyrotropin-releasing hormone (TRH) stimulation test in 12
patients with panic disorder and 10 control subjects. As a group, panic
disorder patients had lower mean TSH and prolactin responses, and female
patients accounted for the lower prolactin response. The clinical and
theoretical implications of these findings are discussed.