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Am J Psychiatry 99:687-691, March 1943
doi: 10.1176/appi.ajp.99.5.687
© 1943 American Psychiatric Association
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THE EFFECT OF ELECTRICALLY AND CHEMICALLY INDUCED CONVULSIONS ON CONDITIONED REFLEXES

M. KESSLER 1, and E. GELLHORN 1

1 Departments of Physiology and Psychiatry, College of Medicine, Chicago, Illinois

Experiments are reported in which a conditioned response to the sound of a bell was established in 18 male rats. This response was then inhibited by lack of reenforcement with the unconditioned stimulus. Although control experiments showed that conditioned responses thus inhibited do not recover spontaneously it was found that the application of one or more metrazol convulsions or of electrically induced convulsions restored temporarily the inhibited conditioned response. The experimentally proved removal of inhibition by "shock treatment" is of interest in view of the effects of the shock treatment in psychoses.







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