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Am J Psychiatry 96:1023-1027, March 1940
doi: 10.1176/appi.ajp.96.5.1023
© 1940 American Psychiatric Association
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FURTHER EXPERIENCES WITH THE USE OF SODIUM DIPHENYL HYDANTOINATE IN THE TREATMENT OF CONVULSIVE DISORDERS

H. HOUSTON MERRITT M. D.1, and TRACY J. PUTNAM M. D.1

1 The Department of Nervous and Mental Diseases, Harvard Medical School, and the Neurological Unit, Boston City Hospital.

In 227 of 267 patients previously refractory to other forms of therapy, sodium diphenyl hydantoinate has been found to be an effective, non-sedative and relatively non-toxic means of controlling or reducing convulsive seizures over periods varying from two months to two years. A more prolonged study on a larger series of cases is necessary to establish its place in the treatment of patients with convulsive seizures.







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