Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Email this article to a Colleague Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to My Articles & Searches Download to citation manager Citing Articles via HighWire Citing Articles via Google Scholar Articles by Zanarini, M. C. Articles by Silk, K. R. Search for Related Content PubMed Citation Articles by Zanarini, M. C. Articles by Silk, K. R. Other Addictive Disorders Borderline Personality Disorders Other Personality Disorders Child Abuse

Prediction of the 10-Year Course of Borderline Personality Disorder

OBJECTIVE: The purpose of this study was to determine the most clinically relevant baseline predictors of time to remission for patients with borderline personality disorder. METHOD: A total of 290 inpatients meeting criteria for both the Revised Diagnostic Interview for Borderlines and DSM-III-R for borderline personality disorder were assessed during their index admission with a series of semistructured interviews and self-report measures. Diagnostic status was reassessed at five contiguous 2-year time periods. Discrete survival analytic methods, which controlled for baseline severity of borderline psychopathology and time, were used to estimate hazard ratios. RESULTS: Eighty-eight percent of the patients with borderline personality disorder studied achieved remission. In terms of time to remission, 39.3% of the 242 patients who experienced a remission of their disorder first remitted by their 2-year follow-up, an additional 22.3% first remitted by their 4-year follow-up, an additional 21.9% by their 6-year follow-up, an additional 12.8% by their 8-year follow-up, and another 3.7% by their 10-year follow-up. Sixteen variables were found to be significant bivariate predictors of earlier time to remission. Seven of these remained significant in multivariate analyses: younger age, absence of childhood sexual abuse, no family history of substance use disorder, good vocational record, absence of an anxious cluster personality disorder, low neuroticism, and high agreeableness. CONCLUSIONS: The results of this study suggest that prediction of time to remission from borderline personality disorder is multifactorial in nature, involving factors that are routinely assessed in clinical practice and factors, particularly aspects of temperament, that are not.

This article has been cited by other articles:

				K. R. Silk Augmenting Psychotherapy for Borderline Personality Disorder: The STEPPS Program Am J Psychiatry, April 1, 2008; 165(4): 413 - 415. [Full Text] [PDF]

				M. C. Zanarini, F. R. Frankenburg, D. B. Reich, K. R. Silk, J. I. Hudson, and L. B. McSweeney The Subsyndromal Phenomenology of Borderline Personality Disorder: A 10-Year Follow-Up Study Am J Psychiatry, June 1, 2007; 164(6): 929 - 935. [Abstract] [Full Text] [PDF]

				P. Tyrer, N. Coombs, F. Ibrahimi, A. Mathilakath, P. Bajaj, M. Ranger, B. Rao, and R. Din Critical developments in the assessment of personality disorder The British Journal of Psychiatry, May 1, 2007; 190(49): s51 - s59. [Abstract] [Full Text] [PDF]

Get information about faster international access.

Privacy Policy

Copyright © 2006 American Psychiatric Association. All rights reserved.

Home | Search | Current Issue | Past Issues | Subscribe | All APPI Journals | Help | Contact Us