Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Email this article to a Colleague Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to My Articles & Searches Download to citation manager Citing Articles via HighWire Citing Articles via Google Scholar Articles by Roberts, L. W. Articles by Hoop, J. Search for Related Content PubMed Citation Articles by Roberts, L. W. Articles by Hoop, J. Informed Consent Other Ethics Issues Schizophrenia Spectrum Disorders Cognition

An Inverse Relationship Between Perceived Harm and Participation Willingness in Schizophrenia Research Protocols

OBJECTIVE: This study attempted to clarify how people with schizophrenia evaluate the potential harm associated with various research-related procedures and how these assessments relate to participation willingness. METHOD: The authors conducted a semistructured interview among participants with schizophrenia. RESULTS: Sixty participants with schizophrenia rated four procedures as harmful (e.g., symptom induction), five procedures as moderately harmful (e.g., being given a placebo), and six procedures as not harmful (e.g., undergoing a physical examination). Rated willingness to participate was inversely related to the participants’ perceptions of harmfulness for all procedures. CONCLUSIONS: In this study, people living with schizophrenia perceived different research procedures as posing different levels of possible harm. Potential harm appears to be an important consideration in protocol enrollment decisions. This work reaffirms the value of clarifying the strengths of seriously ill people who may choose to participate in research.

This article has been cited by other articles:

				R. P. McMahon, D. L. Kelly, D. L. Boggs, L. Li, Q. Hu, J. M. Davis, and W. T. Carpenter Jr. Feasibility of Reducing the Duration of Placebo-Controlled Trials in Schizophrenia Research Schizophr Bull, March 1, 2008; 34(2): 292 - 301. [Abstract] [Full Text] [PDF]

				L. B. Dunn, D. S. Kim, I. E. Fellows, and B. W. Palmer Worth the Risk? Relationship of Incentives to Risk and Benefit Perceptions and Willingness to Participate in Schizophrenia Research Schizophr Bull, February 14, 2008; (2008) sbn003v1. [Abstract] [Full Text] [PDF]

				L. W. Roberts, T. D. Warner, K. G. Hammond, and L. B. Dunn Assessments by Patients With Schizophrenia and Psychiatrists of Relative Risk of Research Procedures Psychiatr Serv, November 1, 2006; 57(11): 1629 - 1635. [Abstract] [Full Text] [PDF]

Get information about faster international access.

Privacy Policy

Copyright © 2006 American Psychiatric Association. All rights reserved.

Home | Search | Current Issue | Past Issues | Subscribe | All APPI Journals | Help | Contact Us