Am J Psychiatry 162:1963-1966, October 2005
doi: 10.1176/appi.ajp.162.10.1963
© 2005 American Psychiatric Association
Face Recognition Memory Deficits and Visual Object Memory Performance in Patients With Schizophrenia and Their Relatives
Monica E. Calkins, Ph.D.,
Ruben C. Gur, Ph.D.,
J. Daniel Ragland, Ph.D., and
Raquel E. Gur, M.D., Ph.D.
OBJECTIVE: Face recognition memory deficits in schizophrenia are attributed to frontotemporal dysfunction. Biological relatives of patients have similar deficits, suggesting genetic susceptibility. Because the impairment may reflect generalized object memory deficits, the authors evaluated both face and visual object recognition. METHOD: The Penn Face Memory Test and Visual Object Learning Test were given to 102 patients with schizophrenia, 60 of their biological relatives, and 135 healthy comparison subjects. RESULTS: Significant immediate and delayed face recognition deficits were observed in patients and their relatives. Although patients were more impaired in visual object memory than comparison subjects, relatives were not. CONCLUSIONS: Face recognition deficits in patients with schizophrenia and their families are not secondary to generalized object memory deficits and may be an endophenotype reflecting frontotemporal impairment.
This article has been cited by other articles:
|
|
|
|
 
S. McLean, B. Grayson, M. Harris, C. Protheroe, M. Woolley, and J. Neill
Isolation rearing impairs novel object recognition and attentional set shifting performance in female rats
J Psychopharmacol,
January 1, 2010;
24(1):
57 - 63.
[Abstract]
[PDF]
|
|
|
|
|
|
|
A. E. Pinkham, N. J. Sasson, M. E. Calkins, J. Richard, P. Hughett, R. E. Gur, and R. C. Gur
The Other-Race Effect in Face Processing Among African American and Caucasian Individuals With Schizophrenia
Am J Psychiatry,
May 1, 2008;
165(5):
639 - 645.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y.-W. Shin, M. H. Na, T. H. Ha, D.-H. Kang, S.-Y. Yoo, and J. S. Kwon
Dysfunction in Configural Face Processing in Patients With Schizophrenia
Schizophr Bull,
May 1, 2008;
34(3):
538 - 543.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. J. Huentelman, A. Papassotiropoulos, D. W. Craig, F. J. Hoerndli, J. V. Pearson, K.-D. Huynh, J. Corneveaux, J. Hanggi, C. R.A. Mondadori, A. Buchmann, et al.
Calmodulin-binding transcription activator 1 (CAMTA1) alleles predispose human episodic memory performance
Hum. Mol. Genet.,
June 15, 2007;
16(12):
1469 - 1477.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. E. Gur, V. L. Nimgaonkar, L. Almasy, M. E. Calkins, J. D. Ragland, M. F. Pogue-Geile, S. Kanes, J. Blangero, and R. C. Gur
Neurocognitive Endophenotypes in a Multiplex Multigenerational Family Study of Schizophrenia
Am J Psychiatry,
May 1, 2007;
164(5):
813 - 819.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. Bromley
Barriers to the Appropriate Clinical Use of Medications That Improve the Cognitive Deficits of Schizophrenia
Psychiatr Serv,
April 1, 2007;
58(4):
475 - 481.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. E. Calkins, D. J. Dobie, K. S. Cadenhead, A. Olincy, R. Freedman, M. F. Green, T. A. Greenwood, R. E. Gur, R. C. Gur, G. A. Light, et al.
The Consortium on the Genetics of Endophenotypes in Schizophrenia: Model Recruitment, Assessment, and Endophenotyping Methods for a Multisite Collaboration
Schizophr Bull,
January 1, 2007;
33(1):
33 - 48.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. E. Gur, M. E. Calkins, R. C. Gur, W. P. Horan, K. H. Nuechterlein, L. J. Seidman, and W. S. Stone
The Consortium on the Genetics of Schizophrenia: Neurocognitive Endophenotypes
Schizophr Bull,
January 1, 2007;
33(1):
49 - 68.
[Abstract]
[Full Text]
[PDF]
|
|
|
Get information about faster international access.
Privacy Policy
Copyright © 2005
American Psychiatric Association.
All rights reserved.
Home
| Search
| Current Issue
| Past Issues
| Subscribe
| All APPI Journals
| Help
| Contact Us
|
