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Is Age at Symptom Onset Associated With Severity of Memory Impairment in Adults With Obsessive-Compulsive Disorder?

OBJECTIVE: Age at onset is a potentially important marker for neurobiological features of obsessive-compulsive disorder (OCD). This study examined the relationship between age at symptom onset and memory impairment in adults with OCD. METHOD: The authors used the Rey-Osterrieth Complex Figure Test and the California Verbal Learning Test to compare memory functioning of 37 adult OCD patients with self-reported childhood onset of symptoms (onset at less than 18 years of age) with that of 31 patients with adult-onset symptoms. RESULTS: No differences were found between the two groups on any of the verbal and nonverbal memory measures. CONCLUSIONS: Self-reported age at symptom onset is not associated with memory performance in adult patients with OCD according to tests previously found to be sensitive to frontal-striatal system dysfunction and impairment in OCD. Such dysfunction appears to be a consistent feature of OCD in adults, regardless of age at initial symptom onset.

This article has been cited by other articles:

				R. M. Roth, D. Milovan, J. Baribeau, and K. O'Connor Neuropsychological Functioning in Early- and Late-Onset Obsessive-Compulsive Disorder J Neuropsychiatry Clin Neurosci, May 1, 2005; 17(2): 208 - 213. [Abstract] [Full Text] [PDF]

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