Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Email this article to a Colleague Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to My Articles & Searches Download to citation manager Citing Articles via HighWire Citing Articles via Google Scholar Articles by Ross, D. E. Articles by Thaker, G. K. Search for Related Content PubMed Citation Articles by Ross, D. E. Articles by Thaker, G. K. Schizophrenia Spectrum Disorders

Association Between Eye Tracking Disorder in Schizophrenia and Poor Sensory Integration

Objective:The authors tested the hypothesis that eye tracking disorder in schizophrenia is associated with neurological signs.Method:The subjects were 93 normal comparison subjects and 59 schizophrenic patients. They were evaluated with the Neurological Evaluation Scale, a standardized rating instrument that assesses sensory integration, motor coordination, sequencing of complex motor acts, and other neurological signs. Also, the schizophrenic patients' smooth-pursuit eye movements were tested in response to a 0.3-Hz sinusoidal target by means of infrared oculography. They were divided into those with (N=18) and without (N=41) eye tracking disorder by using a previously described method, which was based on mixture analysis of the distribution of position root mean square error.Results:The patients with eye tracking disorder had significantly worse performance than the patients without eye tracking disorder with respect to sensory integration, and the effect size was moderate to large. In comparison with the normal subjects, both patient subgroups had significantly worse performance on all of the Neurological Evaluation Scale subscales. Conclusions:Although neurological signs are present generally in schizophrenia, poor sensory integration is particularly pronounced in patients with eye tracking disorder. A review of the literature shows that the two abnormalities have strikingly similar patterns of validators, including 1) familial aggregation, 2) premorbid presence, 3) syndromal specificity, 4) trait status, and 5) association with the deficit syndrome. Poor sensory integration and eye tracking disorder in schizophrenia may be various manifestations of a common, underlying pathophysiological process. Am J Psychiatry 1998; 155: 1352-1357

This article has been cited by other articles:

				P. Dazzan, K. D. Morgan, X. Chitnis, J. Suckling, C. Morgan, P. Fearon, P. K. McGuire, P. B. Jones, J. Leff, and R. M. Murray The Structural Brain Correlates of Neurological Soft Signs in Healthy Individuals Cereb Cortex, August 1, 2006; 16(8): 1225 - 1231. [Abstract] [Full Text] [PDF]

Get information about faster international access.

Privacy Policy

Copyright © 1998 American Psychiatric Association. All rights reserved.

Home | Search | Current Issue | Past Issues | Subscribe | All APPI Journals | Help | Contact Us