|
| | |
|
Am J Psychiatry 1997; 154:1047-1050
Copyright © 1997 by American Psychiatric Association
Anterior cingulate gyrus volume and glucose metabolism in autistic disorder
MM Haznedar, MS Buchsbaum, M Metzger, A Solimando, J Spiegel-Cohen and E Hollander
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029-6574, USA.
OBJECTIVE: This study reports the first paired measurements of glucose
metabolism and volume of the anterior cingulate gyrus in autism. METHOD:
Magnetic resonance imaging (MRI) and positron emission tomography (PET)
scans of seven high-functioning autistic patients and seven sex- and
age-matched normal volunteers were coregistered. After the anterior
cingulate gyri were outlined on the MRI images, the volumes of the
structures were measured and corrected for brain volume. The volumes were
then applied to the PET images and metabolic maps were obtained. RESULTS:
Right anterior cingulate area 24' was significantly smaller in relative
volume, and both area 24 and area 24' were metabolically less active, in
the autistic patients than in the normal subjects. CONCLUSIONS: Autism may
be characterized by structural and functional alterations in the anterior
cingulate gyrus.
This article has been cited by other articles:
|
|
|
|
 
K. N. Thakkar, F. E. Polli, R. M. Joseph, D. S. Tuch, N. Hadjikhani, J. J.S. Barton, and D. S. Manoach
Response monitoring, repetitive behaviour and anterior cingulate abnormalities in ASD
Brain,
June 11, 2008;
(2008)
awn099v1.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Yamasue, O. Abe, M. Suga, H. Yamada, M. A. Rogers, S. Aoki, N. Kato, and K. Kasai
Sex-Linked Neuroanatomical Basis of Human Altruistic Cooperativeness
Cereb Cortex,
January 29, 2008;
(2008)
bhm254v1.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
N. Schmitz, K. Rubia, T. van Amelsvoort, E. Daly, A. Smith, and D. G.M. Murphy
Neural correlates of reward in autism
The British Journal of Psychiatry,
January 1, 2008;
192(1):
19 - 24.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. M. Haznedar, M. S. Buchsbaum, E. A. Hazlett, E. M. LiCalzi, C. Cartwright, and E. Hollander
Volumetric Analysis and Three-Dimensional Glucose Metabolic Mapping of the Striatum and Thalamus in Patients With Autism Spectrum Disorders
Am J Psychiatry,
July 1, 2006;
163(7):
1252 - 1263.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
B. Korkmaz, G. Benbir, and V. Demirbilek
Migration Abnormality in the Left Cingulate Gyrus Presenting With Autistic Disorder
J Child Neurol,
July 1, 2006;
21(7):
600 - 604.
[Abstract]
[PDF]
|
|
|
|
|
|
|
R. L. Doyle, J. Frazier, T. J. Spencer, D. Geller, J. Biederman, and T. Wilens
Donepezil in the Treatment of ADHD-Like Symptoms in Youths With Pervasive Developmental Disorder: A Case Series.
J Atten Disord,
February 1, 2006;
9(3):
543 - 549.
[Abstract]
[PDF]
|
|
|
|
|
|
|
C. Pantelis, M. Yucel, S. J Wood, D. Velakoulis, D. Sun, G. Berger, G. W Stuart, A. Yung, L. Phillips, and P. D McGorry
Structural Brain Imaging Evidence for Multiple Pathological Processes at Different Stages of Brain Development in Schizophrenia
Schizophr Bull,
July 1, 2005;
31(3):
672 - 696.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. Pierce, F. Haist, F. Sedaghat, and E. Courchesne
The brain response to personally familiar faces in autism: findings of fusiform activity and beyond
Brain,
December 1, 2004;
127(12):
2703 - 2716.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. R. Herbert
Neuroimaging in Disorders of Social and Emotional Functioning: What Is the Question?
J Child Neurol,
October 1, 2004;
19(10):
772 - 784.
[Abstract]
[PDF]
|
|
|
|
|
|
|
J. N. Wood
Social Cognition and the Prefrontal Cortex
Behav Cogn Neurosci Rev,
June 1, 2003;
2(2):
97 - 114.
[Abstract]
[PDF]
|
|
|
|
|
|
|
D. G. M. Murphy, H. D. Critchley, N. Schmitz, G. McAlonan, T. van Amelsvoort, D. Robertson, E. Daly, A. Rowe, A. Russell, A. Simmons, et al.
Asperger Syndrome: A Proton Magnetic Resonance Spectroscopy Study of Brain
Arch Gen Psychiatry,
October 1, 2002;
59(10):
885 - 891.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. M. McAlonan, E. Daly, V. Kumari, H. D. Critchley, T. v. Amelsvoort, J. Suckling, A. Simmons, T. Sigmundsson, K. Greenwood, A. Russell, et al.
Brain anatomy and sensorimotor gating in Asperger's syndrome
Brain,
July 1, 2002;
125(7):
1594 - 1606.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. S. New, E. A. Hazlett, M. S. Buchsbaum, M. Goodman, D. Reynolds, V. Mitropoulou, L. Sprung, R. B. Shaw Jr, H. Koenigsberg, J. Platholi, et al.
Blunted Prefrontal Cortical 18Fluorodeoxyglucose Positron Emission Tomography Response to Meta-Chlorophenylpiperazine in Impulsive Aggression
Arch Gen Psychiatry,
July 1, 2002;
59(7):
621 - 629.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
N. J. Rinehart, J. L. Bradshaw, B. J. Tonge, A. V. Brereton, and M. A. Bellgrove
A neurobehavioral examination of individuals with high-functioning autism and Asperger's disorder using a fronto-striatal model of dysfunction.
Behav Cogn Neurosci Rev,
June 1, 2002;
1(2):
164 - 177.
[Abstract]
[PDF]
|
|
|
|
|
|
|
D. K. Sokol, D. W. Dunn, M. Edwards-Brown, and J. Feinberg
Hydrogen Proton Magnetic Resonance Spectroscopy in Autism: Preliminary Evidence of Elevated Choline/Creatine Ratio
J Child Neurol,
April 1, 2002;
17(4):
245 - 249.
[Abstract]
[PDF]
|
|
|
|
|
|
|
T. Suhara, Y. Okubo, F. Yasuno, Y. Sudo, M. Inoue, T. Ichimiya, Y. Nakashima, K. Nakayama, S. Tanada, K. Suzuki, et al.
Decreased Dopamine D2 Receptor Binding in the Anterior Cingulate Cortex in Schizophrenia
Arch Gen Psychiatry,
January 1, 2002;
59(1):
25 - 30.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. D. Critchley, E. M. Daly, E. T. Bullmore, S. C. R. Williams, T. Van Amelsvoort, D. M. Robertson, A. Rowe, M. Phillips, G. McAlonan, P. Howlin, et al.
The functional neuroanatomy of social behaviour: Changes in cerebral blood flow when people with autistic disorder process facial expressions
Brain,
November 1, 2000;
123(11):
2203 - 2212.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Ohnishi, H. Matsuda, T. Hashimoto, T. Kunihiro, M. Nishikawa, T. Uema, and M. Sasaki
Abnormal regional cerebral blood flow in childhood autism
Brain,
September 1, 2000;
123(9):
1838 - 1844.
[Abstract]
[Full Text]
[PDF]
|
|
|
Get information about faster international access.
Privacy Policy
Copyright © 1997
American Psychiatric Association.
All rights reserved.
Home
| Search
| Current Issue
| Past Issues
| Subscribe
| All APPI Journals
| Help
| Contact Us
|
