The American Journal of Psychiatry
Journal Home Search Current Issue Past Issues Subscribe All APPI Journals Help Contact Us
 
Quicksearch
Advanced Search
Or Search All APPI Journals
This Article
* Alert me when this article is cited
* Alert me if a correction is posted
* Citation Map
Services
* Email this article to a Colleague
* Similar articles in this journal
* Similar articles in PubMed
* Alert me to new issues of the journal
* Add to My Articles & Searches
* Download to citation manager
* reprints & permissions
Citing Articles
* Citing Articles via HighWire
* Citing Articles via Google Scholar
Google Scholar
* Articles by Levitan, R. D.
* Articles by Kennedy, S. H.
* Search for Related Content
PubMed
* PubMed Citation
* Articles by Levitan, R. D.
* Articles by Kennedy, S. H.
Related Collections
* Depression
* Epidemiology

Am J Psychiatry 1997; 154:934-940
Copyright © 1997 by American Psychiatric Association


REGULAR ARTICLES

Reversed neurovegetative symptoms of depression: a community study of Ontario

RD Levitan, A Lesage, SV Parikh, P Goering and SH Kennedy
Clarke Institute of Psychiatry, Toronto, Ont., Canada. levitanr@cs.clarke-inst.on.ca

OBJECTIVE: Most research on depression with reversed neurovegetative features (hypersomnia, hyperphagia, and weight gain) has been based on site-specific clinic-based samples. The goal of this study was to delineate the epidemiology of reversed symptoms in a large community sample and to use other symptom patterns for comparison. METHOD: Interviewers assessed 8,116 subjects across Ontario, aged 15-64 years, by using the World Health Organization Composite International Diagnostic Interview. Individuals who met the DSM-III-R criteria for major depression, current or lifetime, were classified into four groups on the basis of lifetime neurovegetative symptoms: episodes of typical symptoms only, episodes of reversed symptoms only, neither type, or both types (fluctuating-symptom group). The groups were compared on demographic characteristics, comorbidity, disability, and health care utilization. RESULTS: Of the 653 individuals with lifetime major depression, 11.3% had episodes of reversed symptoms only, and another 5.8% were classified as fluctuating. Most of the differences among the four groups were due to the unique characteristics of the groups with neither type of episode or a fluctuating pattern; individuals who had experienced only reversed symptoms were remarkably similar to those who had had only typical symptoms. The fluctuating-symptom group had high rates of comorbidity, substance abuse, and health care utilization. CONCLUSIONS: Several popular beliefs about depression with reversed features did not hold true for this community sample. Identifying individuals who fluctuate between reversed and typical episodes may be important in studies of major depression, in particular when reversed neurovegetative symptoms are a consideration.


This article has been cited by other articles:


Home page
Proc. Natl. Acad. Sci. USAHome page
P. W. Gold, M.-L. Wong, D. S. Goldstein, H. K. Gold, D. S. Ronsaville, M. Esler, S. Alesci, A. Masood, J. Licinio, T. D. Geracioti Jr., et al.
Cardiac implications of increased arterial entry and reversible 24-h central and peripheral norepinephrine levels in melancholia
PNAS, June 7, 2005; 102(23): 8303 - 8308.
[Abstract] [Full Text] [PDF]


Home page
Arch Gen PsychiatryHome page
L. S. Matza, D. A. Revicki, J. R. Davidson, and J. W. Stewart
Depression With Atypical Features in the National Comorbidity Survey: Classification, Description, and Consequences
Arch Gen Psychiatry, August 1, 2003; 60(8): 817 - 826.
[Abstract] [Full Text] [PDF]


Home page
Am. J. PsychiatryHome page
R. D. LEVITAN and S. V. PARIKH
Childhood Trauma and Depression
Am J Psychiatry, June 1, 2003; 160(6): 1188 - 1188.
[Full Text]


Home page
Arch Gen PsychiatryHome page
R. D. Levitan, R. B. Jarrett, M. Schaffer, D. McIntire, A. Witt-Browder, D. Kraft, and R. C. Risser
Treatment of Atypical Depression With Cognitive Therapy or Phenelzine
Arch Gen Psychiatry, November 1, 2000; 57(11): 1084 - 1084.
[Full Text] [PDF]


Home page
Am. J. PsychiatryHome page
R. D. Levitan, S. V. Parikh, A. D. Lesage, K. M. Hegadoren, M. Adams, S. H. Kennedy, and P. N. Goering
Major Depression in Individuals With a History of Childhood Physical or Sexual Abuse: Relationship to Neurovegetative Features, Mania, and Gender
Am J Psychiatry, December 1, 1998; 155(12): 1746 - 1752.
[Abstract] [Full Text]


Home page
Am. J. PsychiatryHome page
P. F. Sullivan, R. C. Kessler, and K. S. Kendler
Latent Class Analysis of Lifetime Depressive Symptoms in the National Comorbidity Survey
Am J Psychiatry, October 1, 1998; 155(10): 1398 - 1406.
[Abstract] [Full Text]




Get information about faster international access.

Privacy Policy

Copyright © 1997 American Psychiatric Association. All rights reserved.

Home | Search | Current Issue | Past Issues | Subscribe | All APPI Journals | Help | Contact Us

American Psychiatric Publishing, Inc. American Psychiatric Association
1000 Wilson Boulevard, Suite 1825, Arlington, VA 22209-3901 * 800-368-5777 * appi at psych.org