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Am J Psychiatry 1997; 154:271-273
Copyright © 1997 by American Psychiatric Association
Obsessive-compulsive disorder in patients with schizophrenia or schizoaffective disorder
JL Eisen, DA Beer, MT Pato, TA Venditto and SA Rasmussen
Department of Psychiatry and Human Behavior, Brown University, Providence, R.I, USA.
OBJECTIVE: The authors evaluated the frequency of DSM-III-R obsessive-
compulsive disorder in patients with a primary diagnosis of schizophrenia
or schizoaffective disorder. METHOD: Patients with schizophrenia (N = 52)
or schizoaffective disorder (N = 25) were evaluated for the presence of
obsessions and compulsions by means of the Structured Clinical Interview
for DSM-III-R, the Yale-Brown Obsessive Compulsive Scale, chart review, and
contact with the treating clinicians. RESULTS: Six (7.8%) of the 77
patients met the DSM-III-R criteria for both obsessive-compulsive disorder
and schizophrenia or schizoaffective disorder. CONCLUSIONS: These findings
suggest that obsessive-compulsive disorder occurs in a substantial
percentage of patients with schizophrenia or schizoaffective disorder. The
addition of medications targeted at obsessive-compulsive disorder may be
beneficial to these patients but requires systematic evaluation.
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