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Am J Psychiatry 1996; 153:783-788
Copyright © 1996 by American Psychiatric Association
Quality of life for patients with obsessive-compulsive disorder
LM Koran, ML Thienemann and R Davenport
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, CA, USA.
OBJECTIVE: The health-related quality of life of patients with
obsessive-compulsive disorder was compared to published norms for the
general U.S. population and for patients with either depressive disorders
or diabetes. METHOD: Sixty medication-free outpatients with moderate to
severe obsessive-compulsive disorder were evaluated by using the Structured
Clinical Interview for DSM-III-R and the Yale- Brown Obsessive Compulsive
Scale. Health-related quality of life was measured with the self-rated
Medical Outcomes Study 36-Item Short-Form Health Survey. RESULTS: The
instrumental role performance and social functioning of the patients with
obsessive-compulsive disorder were worse than those of the general
population and of diabetes patients. The more severe the
obsessive-compulsive disorder, the lower were the patients' social
functioning scores, even after depression ratings were controlled for;
scores on instrumental role performance did not correlate with severity of
obsessive-compulsive disorder. The ratings of the obsessive-compulsive
disorder patients on physical health domains resembled those of the general
population and exceeded those of the diabetes patients. The general health
and physical health ratings of the obsessive-compulsive disorder patients
exceeded those of the depressed patients. In mental health domains, after
adjustment for differences in gender distribution, quality of life ratings
were similar for the patients with obsessive-compulsive disorder and those
with depressive disorders. CONCLUSIONS: Moderate to severe obsessive-
compulsive disorder is associated with impaired social functioning and
impaired instrumental role performance, but only impairment in social
functioning is linearly related to severity of obsessive-compulsive
disorder.
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