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Am J Psychiatry 1996; 153:261-263
Copyright © 1996 by American Psychiatric Association


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Acute manic episodes in pregnancy [clinical conference]

M Finnerty, Z Levin and LJ Miller
New York State Psychiatric Institute, NY 10032, USA.

A 33-year-old pregnant woman at 26 weeks gestation, who had a history of bipolar mood disorder, type I, was admitted to the hospital for hypomania and poorly controlled diabetes mellitus. The patient had had her first episode of affective illness at age 28, after the birth of her second child. After an initial postpartum depression, she had cycled into a manic state. She had subsequently been hospitalized seven times for acute mania. A combination of valproate and chlorpromazine had proven effective in managing most of her manic episodes, while her two most severe episodes had been successfully managed with bilateral ECT.


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