Clinical and phenomenological comparisons of late-onset and early-onset depression



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	Articles by Blazer, D. G.

Am J Psychiatry 1995; 152:785-788
Copyright © 1995 by American Psychiatric Association

REGULAR ARTICLES

Clinical and phenomenological comparisons of late-onset and early-onset depression

KR Krishnan, JC Hays, LA Tupler, LK George and DG Blazer
Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, USA.

OBJECTIVE: The authors examined the relationship between age at onset of first depressive episode and clinical features in elderly depressed patients. METHOD: They used data on age at onset and clinical features in 246 elderly depressed patients treated at the National Institute of Mental Health Clinical Research Center for the Study of Depression in Later Life, located at Duke University. RESULTS: Two variables--loss of interest and number of depressive episodes--were related to age at onset in all analyses. CONCLUSIONS: This study confirms the hypothesis that apathy is more prominent in late-onset than in early-onset depression.

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