|
| | |
|
Am J Psychiatry 1995; 152:772-777
Copyright © 1995 by American Psychiatric Association
A case-controlled study of repetitive thoughts and behavior in adults with autistic disorder and obsessive-compulsive disorder
CJ McDougle, LE Kresch, WK Goodman, ST Naylor, FR Volkmar, DJ Cohen and LH Price
Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
OBJECTIVE: The purpose of this study was to investigate the types of
repetitive thoughts and behavior demonstrated by adults with autistic
disorder and compare them with those of age- and sex-matched adults with
obsessive-compulsive disorder. METHOD: Fifty consecutive patients admitted
to the Yale Adult Pervasive Developmental Disorders (Autism) Clinic with a
primary diagnosis of autistic disorder (DSM-III-R and DSM- IV) completed
the symptom checklist of the Yale-Brown Obsessive Compulsive Scale. Types
of current obsessions and compulsions were evaluated. The comparison group
consisted of 50 age- and sex-matched adults with obsessive-compulsive
disorder (without tics) (DSM-III-R and DSM-IV). RESULTS: Direct
discriminant function analysis showed that the patients with autistic
disorder could be distinguished from those with obsessive-compulsive
disorder on the basis of the types of current repetitive thoughts and
behavior that they demonstrated. Compared to the obsessive-compulsive
group, the autistic patients were significantly less likely to experience
thoughts with aggressive, contamination, sexual, religious, symmetry, and
somatic content. Repetitive ordering; hoarding; telling or asking (trend);
touching, tapping, or rubbing; and self-damaging or self-mutilating
behavior occurred significantly more frequently in the autistic patients,
whereas cleaning, checking, and counting behavior was less common in the
autistic group than in the patients with obsessive-compulsive disorder. In
addition, a specific subset of seven obsessive-compulsive variables from
the Yale-Brown Obsessive Compulsive Scale symptom checklist was identified
that reliably predicted membership in the autistic group. CONCLUSIONS:
These results suggest that the repetitive thoughts and behavior
characteristics of autism differ significantly from the
obsessive-compulsive symptoms displayed by patients with
obsessive-compulsive disorder. Future studies are warranted to assess the
treatment response and neurobiological underpinnings of repetitive thoughts
and behavior in patients with autism and obsessive-compulsive disorder.
This article has been cited by other articles:
|
|
|
|
 
K. N. Thakkar, F. E. Polli, R. M. Joseph, D. S. Tuch, N. Hadjikhani, J. J.S. Barton, and D. S. Manoach
Response monitoring, repetitive behaviour and anterior cingulate abnormalities in autism spectrum disorders (ASD)
Brain,
September 1, 2008;
131(9):
2464 - 2478.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Hutton, S. Goode, M. Murphy, A. Le Couteur, and M. Rutter
New-onset psychiatric disorders in individuals with autism
Autism,
July 1, 2008;
12(4):
373 - 390.
[Abstract]
[PDF]
|
|
|
|
|
|
|
Xue Ming, M. Brimacombe, J. Chaaban, B. Zimmerman-Bier, and G. C. Wagner
Autism Spectrum Disorders: Concurrent Clinical Disorders
J Child Neurol,
January 1, 2008;
23(1):
6 - 13.
[Abstract]
[PDF]
|
|
|
|
|
|
|
O. Oner, H. Devrimci-Ozguven, F. Oktem, B. Yagmurlu, B. Baskak, and K.M. Munir
Proton MR Spectroscopy: Higher Right Anterior Cingulate N-Acetylaspartate/Choline Ratio in Asperger Syndrome Compared with Healthy Controls
AJNR Am. J. Neuroradiol.,
September 1, 2007;
28(8):
1494 - 1498.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Bejerot
An autistic dimension: A proposed subtype of obsessive-compulsive disorder
Autism,
March 1, 2007;
11(2):
101 - 110.
[Abstract]
[PDF]
|
|
|
|
|
|
|
J. F. Leckman and Y.-S. Kim
A Primary Candidate Gene for Obsessive-compulsive Disorder.
Arch Gen Psychiatry,
July 1, 2006;
63(7):
717 - 720.
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. J. McDougle, L. Scahill, M. G. Aman, J. T. McCracken, E. Tierney, M. Davies, L. E. Arnold, D. J. Posey, A. Martin, J. K. Ghuman, et al.
Risperidone for the Core Symptom Domains of Autism: Results From the Study by the Autism Network of the Research Units on Pediatric Psychopharmacology
Am J Psychiatry,
June 1, 2005;
162(6):
1142 - 1148.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. J. RUSSELL, D. MATAIX-COLS, M. ANSON, and D. G. M. MURPHY
Obsessions and compulsions in Asperger syndrome and high-functioning autism
The British Journal of Psychiatry,
June 1, 2005;
186(6):
525 - 528.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
U. Chowdhury, I. Frampton, and I. Heyman
Clinical Characteristics of Young People Referred to an Obsessive Compulsive Disorder Clinic in the United Kingdom
Clinical Child Psychology and Psychiatry,
July 1, 2004;
9(3):
395 - 401.
[Abstract]
[PDF]
|
|
|
|
|
|
|
J. Reaven and S. Hepburn
Cognitive-Behavioral Treatment of Obsessive- Compulsive Disorder in a Child with Asperger Syndrome: A Case Report
Autism,
June 1, 2003;
7(2):
145 - 164.
[Abstract]
[PDF]
|
|
|
|
|
|
|
D. G. M. Murphy, H. D. Critchley, N. Schmitz, G. McAlonan, T. van Amelsvoort, D. Robertson, E. Daly, A. Rowe, A. Russell, A. Simmons, et al.
Asperger Syndrome: A Proton Magnetic Resonance Spectroscopy Study of Brain
Arch Gen Psychiatry,
October 1, 2002;
59(10):
885 - 891.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. Hollander, G. DelGiudice-Asch, L. Simon, J. Schmeidler, C. Cartwright, C. M. DeCaria, J. Kwon, C. Cunningham-Rundles, F. Chapman, and J. B. Zabriskie
B Lymphocyte Antigen D8/17 and Repetitive Behaviors in Autism
Am J Psychiatry,
February 1, 1999;
156(2):
317 - 320.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
C. J. McDougle, J. P. Holmes, D. C. Carlson, G. H. Pelton, D. J. Cohen, and L. H. Price
A Double-blind, Placebo-Controlled Study of Risperidone in Adults With Autistic Disorder and Other Pervasive Developmental Disorders
Arch Gen Psychiatry,
July 1, 1998;
55(7):
633 - 641.
[Abstract]
[Full Text]
[PDF]
|
|
|
Get information about faster international access.
Privacy Policy
Copyright © 1995
American Psychiatric Association.
All rights reserved.
Home
| Search
| Current Issue
| Past Issues
| Subscribe
| All APPI Journals
| Help
| Contact Us
|
