|
| | |
|
Am J Psychiatry 1995; 152:1652-1658
Copyright © 1995 by American Psychiatric Association
Psychoactive substance use disorders in adults with attention deficit hyperactivity disorder (ADHD): effects of ADHD and psychiatric comorbidity
J Biederman, T Wilens, E Mick, S Milberger, TJ Spencer and SV Faraone
Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston 02114, USA.
OBJECTIVE: The authors evaluated the association between attention deficit
hyperactivity disorder (ADHD) and psychoactive substance use disorders in
adults with ADHD, attending to comorbidity with mood, anxiety, and
antisocial disorders. It was hypothesized that psychiatric comorbidity
would be a risk factor for psychoactive substance use disorders. METHOD:
Findings for 120 referred adults with a clinical diagnosis of
childhood-onset ADHD were compared with those for non-ADHD adult comparison
subjects (N = 268). All childhood and adult diagnoses were obtained by
structured psychiatric interviews for DSM-III-R. RESULTS: There was a
significantly higher lifetime risk for psychoactive substance use disorders
in the ADHD adults than in the comparison subjects (52% versus 27%).
Although the two groups did not differ in the rate of alcohol use
disorders, the ADHD adults had significantly higher rates of drug and drug
plus alcohol use disorders than the comparison subjects. ADHD significantly
increased the risk for substance use disorders independently of psychiatric
comorbidity. Antisocial disorders significantly increased the risk for
substance use disorders independently of ADHD status. Mood and anxiety
disorders increased the risk for substance use disorders in both the ADHD
and comparison subjects, but more demonstrably in the comparison subjects.
CONCLUSIONS: Although psychiatric comorbidity increased the risk for
psychoactive substance use disorders in adults with ADHD, by itself ADHD
was a significant risk factor for substance use disorders. More information
is needed to further delineate risk and protective factors mediating the
development of substance use disorders in persons with ADHD.
This article has been cited by other articles:
|
|
|
|
 
S. Collins-Chobanian
Analysis of Paul Butler's Race-Based Jury Nullification and His Call to Black Jurors and the African American Community
Journal of Black Studies,
March 1, 2009;
39(4):
508 - 527.
[Abstract]
[PDF]
|
|
|
|
|
|
|
K. Rasmussen and S. Levander
Untreated ADHD in Adults: Are There Sex Differences in Symptoms, Comorbidity, and Impairment?
J Atten Disord,
January 1, 2009;
12(4):
353 - 360.
[Abstract]
[PDF]
|
|
|
|
|
|
|
T. E. Wilens, J. Adamson, M. C. Monuteaux, S. V. Faraone, M. Schillinger, D. Westerberg, and J. Biederman
Effect of Prior Stimulant Treatment for Attention-Deficit/Hyperactivity Disorder on Subsequent Risk for Cigarette Smoking and Alcohol and Drug Use Disorders in Adolescents
Arch Pediatr Adolesc Med,
October 1, 2008;
162(10):
916 - 921.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. H. Kollins
ADHD, Substance Use Disorders, and Psychostimulant Treatment: Current Literature and Treatment Guidelines
J Atten Disord,
September 1, 2008;
12(2):
115 - 125.
[Abstract]
[PDF]
|
|
|
|
|
|
|
M. D. Ohlmeier, K. Peters, B. T. T. Wildt, M. Zedler, M. Ziegenbein, B. Wiese, H. M. Emrich, and U. Schneider
Comorbidity of Alcohol and Substance Dependence with Attention-Deficit/Hyperactivity Disorder (ADHD)
Alcohol Alcohol.,
March 7, 2008;
(2008)
agn014v1.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J.J. Sandra Kooij, A. Marije Boonstra, S.H.N. Swinkels, E. M. Bekker, I. de Noord, and J. K. Buitelaar
Reliability, Validity, and Utility of Instruments for Self-Report and Informant Report Concerning Symptoms of ADHD in Adult Patients
J Atten Disord,
January 1, 2008;
11(4):
445 - 458.
[Abstract]
[PDF]
|
|
|
|
|
|
|
J. Biederman, C. R. Petty, T. E. Wilens, M. G. Fraire, C. A. Purcell, E. Mick, M. C. Monuteaux, and S. V. Faraone
Familial Risk Analyses of Attention Deficit Hyperactivity Disorder and Substance Use Disorders
Am J Psychiatry,
January 1, 2008;
165(1):
107 - 115.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. D. Ohlmeier, K. Peters, A. Kordon, J. Seifert, B. T. Wildt, B. Wiese, M. Ziegenbein, H. M. Emrich, and U. Schneider
Nicotine and alcohol dependence in patients with comorbid attention-deficit/hyperactivity disorder (ADHD)
Alcohol Alcohol.,
November 1, 2007;
42(6):
539 - 543.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. G. Almeida Montes, A. O. Hernandez Garcia, and J. Ricardo-Garcell
ADHD Prevalence in Adult Outpatients With Nonpsychotic Psychiatric Illnesses
J Atten Disord,
September 1, 2007;
11(2):
150 - 156.
[Abstract]
[PDF]
|
|
|
|
|
|
|
G. U. Law, S. Sinclair, and N. Fraser
Children's attitudes and behavioural intentions towards a peer with symptoms of ADHD: does the addition of a diagnostic label make a difference?
J Child Health Care,
June 1, 2007;
11(2):
98 - 111.
[Abstract]
[PDF]
|
|
|
|
|
|
|
A. H. Friedlander, J. A. Yagiela, M. E. Mahler, and R. Rubin
The pathophysiology, medical management and dental implications of adult attention-deficit/hyperactivity disorder
J Am Dent Assoc,
April 1, 2007;
138(4):
475 - 482.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. E. Wilens
Attention Deficit Hyperactivity Disorder and Substance Use Disorders
Am J Psychiatry,
December 1, 2006;
163(12):
2059 - 2063.
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. L. Richards, J. L. Deffenbacher, L. A. Rosen, R. A. Barkley, and T. Rodricks
Driving anger and driving behavior in adults with ADHD.
J Atten Disord,
August 1, 2006;
10(1):
54 - 64.
[Abstract]
[PDF]
|
|
|
|
|
|
|
B. Pierrehumbert, M. Bader, S. Thevoz, A. Kinal, and O. Halfon
Hyperactivity and Attention Problems in a Swiss Sample of School-Aged Children: Effects of School Achievement, Child Gender, and Informants.
J Atten Disord,
August 1, 2006;
10(1):
65 - 76.
[Abstract]
[PDF]
|
|
|
|
|
|
|
T. E. Wilens and J. Biederman
Alcohol, drugs, and attention-deficit/ hyperactivity disorder: a model for the study of addictions in youth
J Psychopharmacol,
July 1, 2006;
20(4):
580 - 588.
[Abstract]
[PDF]
|
|
|
|
|
|
|
J.-W. KIM, C.-S. PARK, J.-W. HWANG, M.-S. SHIN, K.-E HONG, S.-C. CHO, and B.-N. KIM
CLINICAL AND GENETIC CHARACTERISTICS OF KOREAN MALE ALCOHOLICS WITH AND WITHOUT ATTENTION DEFICIT HYPERACTIVITY DISORDER
Alcohol Alcohol.,
July 1, 2006;
41(4):
407 - 411.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. Magnusson, J. Smari, D. Sigurthardottir, G. Baldursson, J. Sigmundsson, K. Kristjansson, S. Sigurthardottir, S. Hreitharsson, S. Sigurbjornsdottir, and O. O. Guthmundsson
Validity of Self-Report and Informant Rating Scales of Adult ADHD Symptoms in Comparison With a Semistructured Diagnostic Interview.
J Atten Disord,
February 1, 2006;
9(3):
494 - 503.
[Abstract]
[PDF]
|
|
|
|
|
|
|
J. J. McGough and R. A. Barkley
Diagnostic Controversies in Adult Attention Deficit Hyperactivity Disorder
Am J Psychiatry,
November 1, 2004;
161(11):
1948 - 1956.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. S. Ercan, H. Coskunol, A. Varan, and K. Toksoz
CHILDHOOD ATTENTION DEFICIT/HYPERACTIVITY DISORDER AND ALCOHOL DEPENDENCE: A 1-YEAR FOLLOW-UP
Alcohol Alcohol.,
July 1, 2003;
38(4):
352 - 356.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Biederman, T. Wilens, E. Mick, S. V. Faraone, W. Weber, S. Curtis, A. Thornell, K. Pfister, J. G. Jetton, and J. Soriano
Is ADHD a Risk Factor for Psychoactive Substance Use Disorders? Finding From a Four-Year Prospective Follow-Up Study
Focus,
April 1, 2003;
1(2):
196 - 204.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Weiss and C. Murray
Assessment and management of attention-deficit hyperactivity disorder in adults
Can. Med. Assoc. J.,
March 18, 2003;
168(6):
715 - 722.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Ernst, S. J. Grant, E. D. London, C. S. Contoreggi, A. S. Kimes, and L. Spurgeon
Decision Making in Adolescents With Behavior Disorders and Adults With Substance Abuse
Am J Psychiatry,
January 1, 2003;
160(1):
33 - 40.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. E. Wilens, S. V. Faraone, J. Biederman, and S. Gunawardene
Does Stimulant Therapy of Attention-Deficit/Hyperactivity Disorder Beget Later Substance Abuse? A Meta-analytic Review of the Literature
Pediatrics,
January 1, 2003;
111(1):
179 - 185.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. P Kafka and J. Hennen
A DSM-IV Axis I Comorbidity Study of Males (n = 120) With Paraphilias and Paraphilia-Related Disorders
Sexual Abuse: A Journal of Research and Treatment,
October 1, 2002;
14(4):
349 - 366.
[Abstract]
[PDF]
|
|
|
|
|
|
|
T.L. Richards, J.L. Deffenbacher, and L.A. Rosen
Driving anger and other driving-related behaviors in high and low ADHD symptom college students
J Atten Disord,
January 1, 2002;
6(1):
25 - 38.
[Abstract]
[PDF]
|
|
|
|
|
|
|
T. E. Wilens, T. J. Spencer, and J. Biederman
A review of the pharmacotherapy of adults with Attention-Deficit/ Hyperactivity Disorder
J Atten Disord,
January 1, 2001;
5(4):
189 - 202.
[Abstract]
[PDF]
|
|
|
|
|
|
|
J. S. Markowitz, C. L. DeVane, D. W. Boulton, Z. Nahas, S. C. Risch, F. Diamond, and K. S. Patrick
Ethylphenidate Formation in Human Subjects after the Administration of a Single Dose of Methylphenidate and Ethanol
Drug Metab. Dispos.,
June 1, 2000;
28(6):
620 - 624.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
B. Eghbalieh, F. M. Crinella, L. E. Hunt, and J. M. Swanson
Prenatal stimulant exposure affects alerting and executive control in six and seven-year-olds
J Atten Disord,
April 1, 2000;
4(1):
5 - 13.
[Abstract]
[PDF]
|
|
|
|
|
|
|
J. Biederman, T. Wilens, E. Mick, T. Spencer, and S. V. Faraone
Pharmacotherapy of Attention-deficit/Hyperactivity Disorder Reduces Risk for Substance Use Disorder
Pediatrics,
August 1, 1999;
104(2):
20e - 20.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
S. Milberger, S. V. Faraone, J. Biederman, M. P. Chu, and T. Wilens
Familial Risk Analysis of the Association Between Attention-Deficit/Hyperactivity Disorder and Psychoactive Substance Use Disorders
Arch Pediatr Adolesc Med,
October 1, 1998;
152(10):
945 - 951.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. J. Garland
Reviews : Pharmacotherapy of adolescent attention deficit hyperactivity disorder: challenges, choices and caveats
J Psychopharmacol,
January 1, 1998;
12(4):
385 - 395.
[Abstract]
[PDF]
|
|
|
|
|
|
|
R.B. Millstein, T.E. Wilens, J. Biederman, and T.J. Spencer
Presenting ADHD symptoms and subtypes in clinically referred adults with ADHD
J Atten Disord,
October 1, 1997;
2(3):
159 - 166.
[Abstract]
|
|
|
|
|
|
|
K. Murphy and R.A. Barkley
Prevalence of DSM-IV symptoms of ADHD in adult licensed drivers: Implications for clinical diagnosis
J Atten Disord,
October 1, 1996;
1(3):
147 - 161.
[Abstract]
|
|
|
|
|
|
|
R.A. Barkley, K. Murphy, and D. Kwasnik
Psychological adjustment and adaptive impairments in young adults with ADHD
J Atten Disord,
April 1, 1996;
1(1):
41 - 54.
[Abstract]
|
|
|
|
|
|
|
ADHD and Substance Use: What Accounts for the Increased Risk?
Journal Watch Psychiatry,
January 1, 1996;
1996(101):
6 - 6.
[Full Text]
|
|
|
Get information about faster international access.
Privacy Policy
Copyright © 1995
American Psychiatric Association.
All rights reserved.
Home
| Search
| Current Issue
| Past Issues
| Subscribe
| All APPI Journals
| Help
| Contact Us
|
