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Am J Psychiatry 1995; 152:137-139
Copyright © 1995 by American Psychiatric Association
Learning and memory in combat veterans with posttraumatic stress disorder
R Yehuda, RS Keefe, PD Harvey, RA Levengood, DK Gerber, J Geni and LJ Siever
Psychiatry Department, Mount Sinai School of Medicine, New York.
OBJECTIVE: The authors investigated a broad range of memory functions for
stimuli unrelated to trauma to determine whether symptoms such as intrusive
memories might reflect an underlying cognitive deficit unrelated to the
psychological content of the traumatic memory in patients with
posttraumatic stress disorder (PTSD). METHOD: The authors measured the
intellectual functioning of 20 male combat veterans with PTSD and 12 normal
comparison subjects using the WAIS and evaluated them for performance on
memory using the California Verbal Learning Test. RESULTS: Veterans with
PTSD showed normal abilities in the functions of initial attention,
immediate memory, cumulative learning, and active interference from
previous learning. However, these veterans showed a circumscribed cognitive
deficit, manifested by the presence of substantial retroactive interference
and revealed by a significant decrement in retention following exposure to
an intervening word list. CONCLUSIONS: The data suggest that patients with
PTSD may have fairly specific deficits in the monitoring and regulation of
memory information.
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