Am J Psychiatry 1994; 151:432-433
Copyright © 1994 by American Psychiatric Association
The contingent negative variation in positive and negative types of schizophrenia
S Oke, R Saatchi, E Allen, NR Hudson and BW Jervis
Mental Health Services, Barrow Hospital, Bristol, U.K.
The authors analyzed the contingent negative variations of 20 medicated
patients with schizophrenia diagnosed according to DSM-III-R and 20 age-
and sex-matched normal comparison subjects. For the patients with
schizophrenia, there were significant correlations between contingent
negative variation amplitude and two items on the Scale for the Assessment
of Negative Symptoms (affective flattening and avolition- apathy) and the
total score on this scale. These findings have implications regarding the
underlying pathology of negative and positive symptoms of schizophrenia.
