Ketoconazole administration in hypercortisolemic depression



	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted
	Citation Map



	Email this article to a Colleague
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Add to My Articles & Searches
	Download to citation manager



	Citing Articles via HighWire
	Citing Articles via Google Scholar



	Articles by Wolkowitz, O. M.
	Articles by Weingartner, H.
	Search for Related Content



	PubMed Citation
	Articles by Wolkowitz, O. M.
	Articles by Weingartner, H.

Am J Psychiatry 1993; 150:810-812
Copyright © 1993 by American Psychiatric Association

REGULAR ARTICLES

Ketoconazole administration in hypercortisolemic depression

OM Wolkowitz, VI Reus, F Manfredi, J Ingbar, L Brizendine and H Weingartner
Department of Psychiatry, University of California, San Francisco.

Ketoconazole, an antiglucocorticoid drug, was administered to 10 hypercortisolemic depressed patients for up to 6 weeks. Three patients dropped out because of side effects or intercurrent illness. The remaining seven had significant ketoconazole-associated decreases in serum cortisol levels and in depression ratings. Antiglucocorticoid agents may be useful probes for investigating the sequelae of hypercortisolemia in patients with major depression.

This article has been cited by other articles:

K. Goodkin
Psychiatric Aspects of HIV Spectrum Disease
Focus, July 1, 2009; 7(3): 303 - 310.
[Abstract] [Full Text] [PDF]

References
PsychiatryOnline CME, May 1, 2007; 2007(1): 2 - 2.
[Full Text]

H. Jahn, M. Schick, F. Kiefer, M. Kellner, A. Yassouridis, and K. Wiedemann
Metyrapone as Additive Treatment in Major Depression: A Double-blind and Placebo-Controlled Trial
Arch Gen Psychiatry, December 1, 2004; 61(12): 1235 - 1244.
[Abstract] [Full Text] [PDF]

C. DeBattista, J. A. Posener, B. M. Kalehzan, and A. F. Schatzberg
Acute Antidepressant Effects of Intravenous Hydrocortisone and CRH in Depressed Patients: A Double-Blind, Placebo-Controlled Study
Am J Psychiatry, August 1, 2000; 157(8): 1334 - 1337.
[Abstract] [Full Text]

O. M. Wolkowitz and V. I. Reus
Treatment of Depression With Antiglucocorticoid Drugs
Psychosom Med, September 1, 1999; 61(5): 698 - 711.
[Abstract] [Full Text] [PDF]

O. M. Wolkowitz, V. I. Reus, A. Keebler, N. Nelson, M. Friedland, L. Brizendine, and E. Roberts
Double-Blind Treatment of Major Depression With Dehydroepiandrosterone
Am J Psychiatry, April 1, 1999; 156(4): 646 - 649.
[Abstract] [Full Text]

E. R. de Kloet, E. Vreugdenhil, M. S. Oitzl, and M. Joëls
Brain Corticosteroid Receptor Balance in Health and Disease
Endocr. Rev., June 1, 1998; 19(3): 269 - 301.
[Abstract] [Full Text]

Get information about faster international access.