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Am J Psychiatry 1993; 150:1707-1711
Copyright © 1993 by American Psychiatric Association
Gender differences in substance use disorders
KT Brady, DE Grice, L Dustan and C Randall
Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425.
OBJECTIVE: The goals of this study were to explore gender differences in
demographic variables, psychiatric comorbidity, and personality disorders
in individuals with substance use disorders. METHOD: A total of 100
treatment-seeking substance users (50 men and 50 women) admitted to a
university-based and a university-affiliated private chemical dependency
hospital were compared with regard to demographic variables and comorbid
psychiatric and personality diagnosis according to the Structured Clinical
Interview for DSM-III-R after 14-21 days in treatment. RESULTS: Men were
significantly more likely to have a higher household income and to be
alcohol dependent. Women were significantly more likely to have another
axis I disorder in addition to substance use disorder, particularly anxiety
disorders, but these gender differences were not substantially different
from the gender prevalence of these disorders in the general population.
Men had more affective disorders relative to women than would be expected
from the general population data. Female alcoholics had substantially more
psychopathology than male alcoholics, and generally these differences were
consistent with the ratios of these disorders in the general population.
For cocaine users, female/male ratios of anxiety and affective disorders
were inconsistent with general population ratios and indicated more
psychopathology than would be expected in male cocaine users. There were no
gender differences in axis II diagnoses. CONCLUSIONS: Some of the gender
differences in psychopathology in substance users are at odds with gender
differences for psychopathology in the general population. Further
exploration of these differences could have important theoretical and
treatment implications.
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