
Am J Psychiatry 1992; 149:689-690
Copyright © 1992 by American Psychiatric Association
Weight gain among schizophrenic patients treated with clozapine
JS Lamberti, T Bellnier and SB Schwarzkopf
Rochester Psychiatric Center, University of Rochester School of Medicine and Dentistry, NY.
A retrospective chart review was used to assess weight changes in 36
chronic schizophrenic inpatients who were treated with clozapine after
being treated with standard neuroleptics. The average weight gain during 6
months of clozapine treatment was 16.9 lb; 75.0% of the patients gained at
least 10 lb. The results confirm previous findings of clozapine-associated
weight gain.
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