Agitation and postdexamethasone cortisol levels in Alzheimer's disease



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	Articles by Davis, K. L.

Am J Psychiatry 1992; 149:546-548
Copyright © 1992 by American Psychiatric Association

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Agitation and postdexamethasone cortisol levels in Alzheimer's disease

BA Lawlor, G Tsuboyama, T Ryan, RC Mohs, BM Davis, M Davidson, S Gabriel and KL Davis
Department of Psychiatry, Mount Sinai School of Medicine, New York, N.Y.

The clinical correlates of hypothalamic-pituitary-adrenal (HPA) functioning were examined in 29 patients with probable Alzheimer's disease. The 8:00 a.m. postdexamethasone cortisol levels of these patients were highly correlated with higher agitation scores but not with the degree of depressed mood or memory impairment. The possible neural basis for the association between hypercortisolism and behavioral disturbance in Alzheimer's disease warrants further exploration and replication.

This article has been cited by other articles:

M. Kirby and B. A. Lawlor
Biologic Markers and Neurochemical Correlates of Agitation and Psychosis in Dementia
J Geriatr Psychiatry Neurol, October 1, 1995; 8(1): S2 - S7.
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