Am J Psychiatry 1991; 148:1240-1242
Copyright © 1991 by American Psychiatric Association

REGULAR ARTICLES

Elevated medial-frontal cerebral blood flow in obsessive-compulsive patients: a SPECT study

SR Machlin, GJ Harris, GD Pearlson, R Hoehn-Saric, P Jeffery and EE Camargo
Department of Psychiatry and Behavioral Sciences, Johns Hopkins Medical Institutions, Baltimore, MD.

Regional cerebral blood flow was measured with single photon emission computed tomography in 10 obsessive-compulsive patients and eight comparison subjects. The patients had a significantly higher ratio of medial-frontal to whole cortex blood flow; this was unrelated to symptom severity but was correlated negatively with anxiety. No differences in orbital-frontal blood flow were found.

This article has been cited by other articles:

				A. Borkowska, E. Pilaczynska, and J. K. Rybakowski The Frontal Lobe Neuropsychological Tests in Patients With Schizophrenia and/or Obsessive-Compulsive Disorder J Neuropsychiatry Clin Neurosci, August 1, 2003; 15(3): 359 - 362. [Abstract] [Full Text] [PDF]

				E. E. Camargo Brain SPECT in Neurology and Psychiatry J. Nucl. Med., April 1, 2001; 42(4): 611 - 623. [Abstract] [Full Text]

				I. Litvan, J. S. Paulsen, M. S. Mega, and J. L. Cummings Neuropsychiatric Assessment of Patients With Hyperkinetic and Hypokinetic Movement Disorders Arch Neurol, October 1, 1998; 55(10): 1313 - 1319. [Abstract] [Full Text] [PDF]

Get information about faster international access.

Privacy Policy

Copyright © 1991 American Psychiatric Association. All rights reserved.

Home | Search | Current Issue | Past Issues | Subscribe | All APPI Journals | Help | Contact Us