Am J Psychiatry 1991; 148:1064-1067
Copyright © 1991 by American Psychiatric Association
Fluoxetine in the treatment of borderline and schizotypal personality disorders
PJ Markovitz, JR Calabrese, SC Schulz and HY Meltzer
Department of Psychiatry, University Hospitals of Cleveland, OH 44106.
Twenty-two patients meeting the criteria for borderline or schizotypal
personality disorder or both participated in a prospective, nonblind 12-
week trial of fluoxetine. There were significant reductions in self- injury
and in scores on the Hopkins Symptom Checklist regardless of diagnosis. The
results suggest that controlled trials of fluoxetine and investigations of
the serotonergic system in these disorders would be useful.
