|
| | |
|
Am J Psychiatry 1991; 148:306-317
Copyright © 1991 by American Psychiatric Association
Self-injurious behavior: a review of the behavior and biology of self- mutilation
RM Winchel and M Stanley
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY.
OBJECTIVE: The authors describe the clinical characteristics of self-
injurious behavior, giving special emphasis to self-injurious behavior
occurring among individuals with character disorders. DATA COLLECTION: They
review data suggesting the involvement of serotonergic, dopaminergic, and
opiate neurotransmitter systems in the expression of self-injurious
behavior. FINDINGS: Self-injurious behavior occurs among mentally retarded
individuals, psychotic patients, prison populations, and individuals with
severe character disorders. Although theoretical psychological models of
self-injurious behavior are helpful in understanding the patient's
experience of self-injury, no generally useful therapeutic approach has yet
evolved from these models. Data derived from animal models and treatment
studies suggest the involvement of opiatergic and dopaminergic mechanisms
in self-injury among the mentally retarded. Serotonergic influences on
self-injurious behavior may be present in varying forms of this behavior.
The scientific literature on the benefits of pharmacological agents for
mentally retarded individuals is beset with a number of problems. Support
is emerging, however, for the use of lithium and carbamazepine with
self-injuring mentally retarded patients, and some behavioral interventions
appear to be successful for mentally retarded individuals. Self-injuring
patients with borderline personality disorder may benefit from milieu
treatment. CONCLUSIONS: Although no form of treatment has yet been
demonstrated to be of general benefit, the literature suggests that
therapeutic trials with dopamine antagonists, serotonin reuptake
inhibitors, and opiate antagonists may be of value.
This article has been cited by other articles:
|
|
|
|
 
A. M. Muehlmann, B. D. Brown, and D. P. Devine
Pemoline (2-Amino-5-phenyl-1,3-oxazol-4-one)-induced Self-Injurious Behavior: A Rodent Model of Pharmacotherapeutic Efficacy
J. Pharmacol. Exp. Ther.,
January 1, 2008;
324(1):
214 - 223.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Reed, A. Russell, K. Xenitidis, and D. G. M. Murphy
People with learning disabilities in a low secure in-patient unit: comparison of offenders and non-offenders
The British Journal of Psychiatry,
December 1, 2004;
185(6):
499 - 504.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. G. Noll, L. A. Horowitz, G. A. Bonanno, P. K. Trickett, and F. W. Putnam
Revictimization and Self-Harm in Females Who Experienced Childhood Sexual Abuse: Results from a Prospective Study
J Interpers Violence,
December 1, 2003;
18(12):
1452 - 1471.
[Abstract]
[PDF]
|
|
|
|
|
|
|
J. Zislin, G. Katz, S. Raskin, Z. Strauss, A. Teitelbaum, and R. Durst
Male Genital Self-Mutilation in the Context of Religious Belief: The Jerusalem Syndrome
Transcultural Psychiatry,
June 1, 2002;
39(2):
257 - 264.
[PDF]
|
|
|
|
|
|
|
S. N. Shaw
Shifting Conversations on Girls' and Women's Self-Injury: An Analysis of the Clinical Literature in Historical Context
Feminism Psychology,
May 1, 2002;
12(2):
191 - 219.
[Abstract]
[PDF]
|
|
|
|
|
|
|
U. SACHSSE, S. VON DER HEYDE, and G. HUETHER
Stress Regulation and Self-Mutilation
Am J Psychiatry,
April 1, 2002;
159(4):
672 - 672.
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Paul, K. Schroeter, B. Dahme, and D. O. Nutzinger
Self-Injurious Behavior in Women With Eating Disorders
Am J Psychiatry,
March 1, 2002;
159(3):
408 - 411.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
W Matthews and D. Wallis
Patterns of self-inflicted injury
Trauma,
January 1, 2002;
4(1):
17 - 20.
[Abstract]
[PDF]
|
|
|
|
|
|
|
H. A. Jinnah, S. Yitta, T. Drew, B. S. Kim, J. E. Visser, and J. D. Rothstein
Calcium channel activation and self-biting in mice
PNAS,
December 21, 1999;
96(26):
15228 - 15232.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
I. BARAL, K. KORA, S. YUKSEL, and U. SEZGIN
Self-Mutilating Behavior of Sexually Abused Female Adults in Turkey
J Interpers Violence,
August 1, 1998;
13(4):
427 - 437.
[Abstract]
|
|
|
|
|
|
|
K. Epps
The Use of Secure Accommodation for Adolescent Girls who Engage in Severe and Repetitive Self-Injurious Behaviour
Clinical Child Psychology and Psychiatry,
October 1, 1997;
2(4):
539 - 552.
[Abstract]
|
|
|
|
|
|
|
C. Yokoyama and H. Okamura
Self-Injurious Behavior and Dopaminergic Neuron System in Neonatal 6-Hydroxydopamine-Lesioned Rat: 1. Dopaminergic Neurons and Receptors
J. Pharmacol. Exp. Ther.,
February 1, 1997;
280(2):
1016 - 1030.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
D. Dossetor
The Hit and Miss of Magic Bullets: A Guide to Psychotropic Medication for Young People with Intellectual Handicap
Clinical Child Psychology and Psychiatry,
January 1, 1997;
2(1):
65 - 93.
[Abstract]
|
|
|
|
|
|
|
J. Turk
Working with Parents of Children who have Severe Learning Disabilities
Clinical Child Psychology and Psychiatry,
October 1, 1996;
1(4):
581 - 596.
[Abstract]
|
|
|
|
|
|
|
G. Hagen, A. Sky, and G. T. Grossberg
Self-injurious behavior in Alzheimer's disease
American Journal of Alzheimer's Disease and Other Dementias,
November 1, 1992;
7(6):
21 - 22.
[Abstract]
[PDF]
|
|
|
Get information about faster international access.
Privacy Policy
Copyright © 1991
American Psychiatric Association.
All rights reserved.
Home
| Search
| Current Issue
| Past Issues
| Subscribe
| All APPI Journals
| Help
| Contact Us
|
