Am J Psychiatry 1991; 148:1577-1579
Copyright © 1991 by American Psychiatric Association
CT scan abnormalities and outcome of chronic schizophrenia
A Vita, M Dieci, GM Giobbio, P Azzone, M Garbarini, E Sacchetti, BM Cesana and CL Cazzullo
Schizophrenia Research Center, University of Milan, Italy.
The authors evaluated the relationship between brain morphological
characteristics assessed by means of computerized tomography and the 2-
year clinical and social outcomes of 18 patients with chronic
schizophrenia. Cerebral structural abnormalities, especially cortical
atrophy, were associated with a poorer outcome in several areas of clinical
and social functioning.