
|
|  | |
|
Am J Psychiatry 1991; 148:1501-1504
Copyright © 1991 by American Psychiatric Association
The family history method: whose psychiatric history is measured?
KS Kendler, JL Silberg, MC Neale, RC Kessler, AC Heath and LJ Eaves
Department of Psychiatry, Medical College of Virginia/Virginia Commonwealth University, Richmond 23298-0710.
OBJECTIVE: The family history method, in which an informant is asked about
the history of psychiatric illness in relatives, is widely used in
psychiatric research. Previous research has examined the influence on
family history information of characteristics of the relative. In this
report, the authors seek to clarify the impact on family history reporting
of the psychiatric history of the informant. METHOD: Both members of female
twin pairs from a population-based twin registry were asked about the
history of major depression, generalized anxiety disorder, and alcoholism
in their mother and father. The authors examined twin pairs discordant for
each of the three diagnoses and predicted that the affected twin would
report higher rates of the same disorder in her parent than would the
unaffected twin. RESULTS: Twins with a history of major depression or
generalized anxiety disorder but not twins with alcoholism were
significantly more likely to report the same disorder in their parents than
were their unaffected co-twins. CONCLUSIONS: For major depression and
generalized anxiety disorder, a family history diagnosis appears to reflect
the psychiatric history of both the relative and the informant. Caution may
be needed in the interpretation of results based on the family history
method, although the magnitude of this problem may be attenuated by the use
of multiple informants.
This article has been cited by other articles:

|
 |

|
 |
 
J. I. Hudson, J. K. Lalonde, J. M. Berry, L. J. Pindyck, C. M. Bulik, S. J. Crow, S. L. McElroy, N. M. Laird, M. T. Tsuang, B. T. Walsh, et al.
Binge-eating disorder as a distinct familial phenotype in obese individuals.
Arch Gen Psychiatry,
March 1, 2006;
63(3):
313 - 319.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
H. F. COELHO, P. J. COOPER, and L. MURRAY
Impact of psychiatric disturbance on identifying psychiatric disorder in relatives: study of mothers and daughters
The British Journal of Psychiatry,
March 1, 2006;
188(3):
288 - 289.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
D. N. Klein, S. A. Shankman, P. M. Lewinsohn, P. Rohde, and J. R. Seeley
Family Study of Chronic Depression in a Community Sample of Young Adults
Am J Psychiatry,
April 1, 2004;
161(4):
646 - 653.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
D. B. Clark, J. Cornelius, D. S. Wood, and M. Vanyukov
Psychopathology Risk Transmission in Children of Parents With Substance Use Disorders
Am J Psychiatry,
April 1, 2004;
161(4):
685 - 691.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
T. D. Wade, C. M. Bulik, C. A. Prescott, and K. S. Kendler
Sex Influences on Shared Risk Factors for Bulimia Nervosa and Other Psychiatric Disorders
Arch Gen Psychiatry,
March 1, 2004;
61(3):
251 - 256.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
R. Lieb, B. Isensee, M. Hofler, H. Pfister, and H.-U. Wittchen
Parental Major Depression and the Risk of Depression and Other Mental Disorders in Offspring: A Prospective-Longitudinal Community Study
Arch Gen Psychiatry,
April 1, 2002;
59(4):
365 - 374.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
R. Heun, A. Papassotiropoulos, F. Jessen, W. Maier, and J. C. S. Breitner
A Family Study of Alzheimer Disease and Early- and Late-Onset Depression in Elderly Patients
Arch Gen Psychiatry,
February 1, 2001;
58(2):
190 - 196.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
D. N. Klein, P. M. Lewinsohn, J. R. Seeley, and P. Rohde
A Family Study of Major Depressive Disorder in a Community Sample of Adolescents
Arch Gen Psychiatry,
January 1, 2001;
58(1):
13 - 20.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
M. M. Weissman, P. Wickramaratne, P. Adams, S. Wolk, H. Verdeli, and M. Olfson
Brief Screening for Family Psychiatric History: The Family History Screen
Arch Gen Psychiatry,
July 1, 2000;
57(7):
675 - 682.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
R. C. Kessler, M. B. Stein, and P. Berglund
Social Phobia Subtypes in the National Comorbidity Survey
Am J Psychiatry,
May 1, 1998;
155(5):
613 - 619.
[Abstract]
[Full Text]
|
 |
|
Get information about faster international access.
a>
Privacy Policy
Copyright © 1991
American Psychiatric Association.
All rights reserved.
Home
| Search
| Current Issue
| Past Issues
| Subscribe
| All APPI Journals
| Help
| Contact Us
|